LKB1 Protein (AA 1-433) (His tag)
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- Target See all LKB1 (STK11) Proteins
- LKB1 (STK11) (serine/threonine Kinase 11 (STK11))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-433
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This LKB1 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- MGSSHHHHHH SSGLVPRGSH MGSMEVVDPQ QLGMFTEGEL MSVGMDTFIH RIDSTEVIYQ PRRKRAKLIG KYLMGDLLGE GSYGKVKEVL DSETLCRRAV KILKKKKLRR IPNGEANVKK EIQLLRRLRH KNVIQLVDVL YNEEKQKMYM VMEYCVCGMQ EMLDSVPEKR FPVCQAHGYF CQLIDGLEYL HSQGIVHKDI KPGNLLLTTG GTLKISDLGV AEALHPFAAD DTCRTSQGSP AFQPPEIANG LDTFSGFKVD IWSAGVTLYN ITTGLYPFEG DNIYKLFENI GKGSYAIPGD CGPPLSDLLK GMLEYEPAKR FSIRQIRQHS WFRKKHPPAE APVPIPPSPD TKDRWRSMTV VPYLEDLHGA DEDEDLFDIE DDIIYTQDFT VPGQVPEEEA SHNGQRRGLP KAVCMNGTEA AQLSTKSRAE GRAPNPARKA CSASSKIRRL SACKQQ
- Purity
- > 85 % by SDS - PAGE
- Top Product
- Discover our top product STK11 Protein
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serine/threonine Kinase 11 (STK11) (AA 1-433) (Active) protein (GST tag)
STK11 Origin: Human Host: Insect cells (Sf21) Recombinant SDS, Func Active
serine/threonine Kinase 11 (STK11) (AA 30-152) protein (His-IF2DI Tag)STK11 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
serine/threonine Kinase 11 (STK11) (AA 321-433) protein (GST tag)STK11 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
serine/threonine Kinase 11 (STK11) (AA 1-433) protein (GST tag)STK11 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
serine/threonine Kinase 11 (STK11) (AA 1-430) protein (His tag)Crystallography grade STK11 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
serine/threonine Kinase 11 (STK11) (AA 1-433) protein (His tag)Crystallography grade STK11 Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
serine/threonine Kinase 11 (STK11) (AA 1-429), (partial) protein (His-SUMO Tag)STK11 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % SDS
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Comment
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Denatured
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 mg/mL
- Buffer
- Liquid. In 20 mM Tris-HCl buffer ( pH 8.0) containing 10 % Glycerol
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
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- Target
- LKB1 (STK11) (serine/threonine Kinase 11 (STK11))
- Alternative Name
- STK11 (STK11 Products)
- Synonyms
- pjs Protein, LKB1 Protein, XEEK1 Protein, Stk11 Protein, PJS Protein, hLKB1 Protein, AA408040 Protein, Lkb1 Protein, Par-4 Protein, R75140 Protein, mLKB1 Protein, wu:fj61a05 Protein, zgc:110180 Protein, xeek1 Protein, serine/threonine kinase 11 Protein, polarization-related protein LKB1 Protein, serine/threonine kinase 11 L homeolog Protein, STK11 Protein, stk11 Protein, LOC662493 Protein, Stk11 Protein, stk11.L Protein
- Background
- SK11 is a member of the serine/threonine kinase family, regulates cell polarity and functions as a tumor suppressor. Mutations in this gene have been associated with Peutz-Jeghers syndrome, an autosomal dominant disorder characterized by the growth of polyps in the gastrointestinal tract, pigmented macules on the skin and mouth, and other neoplasms. Recombinant human STK11 protein, fused to His-tag at N-terminus, was expressed in E.coli.
- Molecular Weight
- 51.0kDa (456aa)
- NCBI Accession
- NP_000446
- UniProt
- Q15831
- Pathways
- AMPK Signaling, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process, Warburg Effect
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