UGT1A1 Protein (AA 26-490) (His tag)
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- Target See all UGT1A1 Proteins
- UGT1A1 (UDP Glucuronosyltransferase 1 Family, Polypeptide A1 (UGT1A1))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 26-490
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This UGT1A1 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- MGSSHHHHHH SSGLVPRGSH MGSHAGKILL IPVDGSHWLS MLGAIQQLQQ RGHEIVVLAP DASLYIRDGA FYTLKTYPVP FQREDVKESF VSLGHNVFEN DSFLQRVIKT YKKIKKDSAM LLSGCSHLLH NKELMASLAE SSFDVMLTDP FLPCSPIVAQ YLSLPTVFFL HALPCSLEFE ATQCPNPFSY VPRPLSSHSD HMTFLQRVKN MLIAFSQNFL CDVVYSPYAT LASEFLQREV TVQDLLSSAS VWLFRSDFVK DYPRPIMPNM VFVGGINCLH QNPLSQEFEA YINASGEHGI VVFSLGSMVS EIPEKKAMAI ADALGKIPQT VLWRYTGTRP SNLANNTILV KWLPQNDLLG HPMTRAFITH AGSHGVYESI CNGVPMVMMP LFGDQMDNAK RMETKGAGVT LNVLEMTSED LENALKAVIN DKSYKENIMR LSSLHKDRPV EPLDLAVFWV EFVMRHKGAP HLRPAAHDLT WYQYHSLD
- Purity
- > 90 % by SDS - PAGE
- Top Product
- Discover our top product UGT1A1 Protein
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UDP Glucuronosyltransferase 1 Family, Polypeptide A1 (UGT1A1) (AA 54-159) protein (GST tag)
UGT1A1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
UDP Glucuronosyltransferase 1 Family, Polypeptide A1 (UGT1A1) (AA 26-533) protein (rho-1D4 tag)Crystallography grade UGT1A1 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
UDP Glucuronosyltransferase 1 Family, Polypeptide A1 (UGT1A1) (AA 26-533) protein (His tag)UGT1A1 Origin: Human Host: Yeast Recombinant > 90 % SDS
UDP Glucuronosyltransferase 1 Family, Polypeptide A1 (UGT1A1) protein (Myc-DYKDDDDK Tag)UGT1A1 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Comment
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Denature
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Liquid, In 20 mM Tris-HCl ( pH 8.0) containing 10 % glycerol
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
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- Target
- UGT1A1 (UDP Glucuronosyltransferase 1 Family, Polypeptide A1 (UGT1A1))
- Alternative Name
- uGT1A1 (UGT1A1 Products)
- Synonyms
- BILIQTL1 Protein, GNT1 Protein, HUG-BR1 Protein, UDPGT Protein, UDPGT 1-1 Protein, UGT1 Protein, UGT1A Protein, Gnt1 Protein, UGT1A01 Protein, Udpgt-1a Protein, UgtBr1 Protein, Udpgt Protein, Ugt1 Protein, zgc:123097 Protein, UDP glucuronosyltransferase family 1 member A1 Protein, UDP glucuronosyltransferase 1 family, polypeptide A1 Protein, UDP-glucuronosyltransferase 1-1 Protein, UDP-glucuronosyltransferase Protein, UDP-glucuronosyltransferase 1-6 Protein, UDP glucuronosyltransferase 1 family polypeptide a1 Protein, UGT1A1 Protein, Ugt1a1 Protein, LOC100065342 Protein, LOC100125517 Protein, LOC100229734 Protein, LOC100405984 Protein, LOC100511479 Protein, ugt1a1 Protein
- Background
- UGT1A1 also known as uDP-glucuronosyltransferase 1-1. uGT1A1 is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. It is also able to catalyze glucuronidation of 17beta-estradiol, 17alpha-ethinylestradiol, 1-hydroxypyrene, 4-methylumbelliferone, 1-naphthol, paranitrophenol, scopoletin, and umbelliferone. Recombinant human uGT1A1, fused to His-tag at N-terminus, was expressed in E.coli.
- Molecular Weight
- 54.7kDa (488aa)
- NCBI Accession
- NP_000454
- UniProt
- P22309
- Pathways
- Steroid Hormone Biosynthesis, Regulation of Lipid Metabolism by PPARalpha
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