CHRNA3 Protein (AA 32-240) (His tag)
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- Target See all CHRNA3 Proteins
- CHRNA3 (Cholinergic Receptor, Nicotinic, alpha 3 (Neuronal) (CHRNA3))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 32-240
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This CHRNA3 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- MGSSHHHHHH SSGLVPRGSH MGSSEAEHRL FERLFEDYNE IIRPVANVSD PVIIHFEVSM SQLVKVDEVN QIMETNLWLK QIWNDYKLKW NPSDYGGAEF MRVPAQKIWK PDIVLYNNAV GDFQVDDKTK ALLKYTGEVT WIPPAIFKSS CKIDVTYFPF DYQNCTMKFG SWSYDKAKID LVLIGSSMNL KDYWESGEWA IIKAPGYKHD IKYNCCEEIY PDITYSLYIR RL
- Purity
- > 80 % by SDS - PAGE
- Top Product
- Discover our top product CHRNA3 Protein
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Cholinergic Receptor, Nicotinic, alpha 3 (Neuronal) (CHRNA3) (AA 1-489) protein (GST tag)
CHRNA3 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Cholinergic Receptor, Nicotinic, alpha 3 (Neuronal) (CHRNA3) (AA 32-141) protein (GST tag)CHRNA3 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Cholinergic Receptor, Nicotinic, alpha 3 (Neuronal) (CHRNA3) (AA 26-234) protein (His tag)Crystallography grade CHRNA3 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Cholinergic Receptor, Nicotinic, alpha 3 (Neuronal) (CHRNA3) (AA 329-477) protein (His tag)Crystallography grade CHRNA3 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Cholinergic Receptor, Nicotinic, alpha 3 (Neuronal) (CHRNA3) (AA 323-471) protein (His tag)Crystallography grade CHRNA3 Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Cholinergic Receptor, Nicotinic, alpha 3 (Neuronal) (CHRNA3) (AA 32-505) protein (rho-1D4 tag)Crystallography grade CHRNA3 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Cholinergic Receptor, Nicotinic, alpha 3 (Neuronal) (CHRNA3) (AA 26-499) protein (rho-1D4 tag)Crystallography grade CHRNA3 Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Comment
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Denatured
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Liquid. In 20 mM Tris-HCl buffer( pH 8.0) containing 10 % glycerol
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
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- Target
- CHRNA3 (Cholinergic Receptor, Nicotinic, alpha 3 (Neuronal) (CHRNA3))
- Alternative Name
- CHRNA3 (CHRNA3 Products)
- Synonyms
- LNCR2 Protein, NACHRA3 Protein, PAOD2 Protein, (a)3 Protein, A730007P14Rik Protein, Acra-3 Protein, Acra3 Protein, cholinergic receptor nicotinic alpha 3 subunit Protein, cholinergic receptor, nicotinic, alpha polypeptide 3 Protein, CHRNA3 Protein, Chrna3 Protein
- Background
- CHRNA3 also known as neuronal acetylcholine receptor subunit alpha-3 isoform 1 is a member of the nicotinic acetylcholine receptor family of proteins. Members of this family of proteins form pentameric complexes comprised of both alpha and beta subunits. CHRNA3 is a ligand-gated ion channel that likely plays a role in neurotransmission. CHRNA3 have been associated with an increased risk of smoking initiation and an increased susceptibility to lung cancer. Alternatively spliced transcript variants have been described. Recombinant human CHRNA3 protein, fused to His-tag at N-terminus, was expressed in E.coli.
- Molecular Weight
- 27kDa (232aa)
- NCBI Accession
- NP_000734
- UniProt
- P32297
- Pathways
- Synaptic Membrane
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