Phosphoglucomutase 1 Protein (PGM1) (AA 1-562) (His tag)

Catalog No. ABIN5854329

Product Details

Target: Phosphoglucomutase 1 (PGM1)

Protein Type: Recombinant

Protein Characteristics: AA 1-562

Origin: Human

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This Phosphoglucomutase 1 protein is labelled with His tag.

Application: SDS-PAGE (SDS)

Sequence: MGSSHHHHHH SSGLVPRGSH MGSMVKIVTV KTQAYQDQKP GTSGLRKRVK VFQSSANYAE NFIQSIISTV EPAQRQEATL VVGGDGRFYM KEAIQLIARI AAANGIGRLV IGQNGILSTP AVSCIIRKIK AIGGIILTAS HNPGGPNGDF GIKFNISNGG PAPEAITDKI FQISKTIEEY AVCPDLKVDL GVLGKQQFDL ENKFKPFTVE IVDSVEAYAT MLRSIFDFSA LKELLSGPNR LKIRIDAMHG VVGPYVKKIL CEELGAPANS AVNCVPLEDF GGHHPDPNLT YAADLVETMK SGEHDFGAAF DGDGDRNMIL GKHGFFVNPS DSVAVIAANI FSIPYFQQTG VRGFARSMPT SGALDRVASA TKIALYETPT GWKFFGNLMD ASKLSLCGEE SFGTGSDHIR EKDGLWAVLA WLSILATRKQ SVEDILKDHW QKYGRNFFTR YDYEEVEAEG ANKMMKDLEA LMFDRSFVGK QFSANDKVYT VEKADNFEYS DPVDGSISRN QGLRLIFTDG SRIVFRLSGT GSAGATIRLY IDSYEKDVAK INQDPQVMLA PLISIALKVS QLQERTGRTA PTVIT

Purity: > 95 % by SDS - PAGE

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. In Phosphate Buffered Saline(  pH 7.4) containing 10 % glycerol

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.

Target Details

Target: Phosphoglucomutase 1 (PGM1)

Alternative Name: PGM1 (PGM1 Products)

Synonyms: CDG1T Protein, GSD14 Protein, ARABIDOPSIS THALIANA PHOSPHOGLUCOMUTASE Protein, ATPGMP Protein, MIO24.4 Protein, MIO24_4 Protein, PGM1 Protein, PHOSPHOGLUCOMUTASE Protein, STARCH-FREE 1 Protein, STF1 Protein, phosphoglucomutase Protein, PSPTO3035 Protein, CMS0426 Protein, 3230402E02Rik Protein, Pgm-1 Protein, Pgm2 Protein, zgc:63718 Protein, phosphoglucomutase-1 Protein, pgm2 Protein, PGM Protein, PGM 1 Protein, phosphoglucomutase 1 Protein, hypothetical protein Protein, phosphoglucomutase Protein, phosphoglucomutase alpha-D-glucose phosphate-specific Pgm Protein, phosphoglucomutase, alpha-D-glucose phosphate-specific Protein, phosphoglucomutase 1 L homeolog Protein, PGM1 Protein, R05F9.6 Protein, PGM Protein, pgm Protein, STY0736 Protein, PMI_RS02700 Protein, Pgm1 Protein, pgm1 Protein, LOC542721 Protein, pgm1.L Protein

Background: PGM1 also known as Phosphoglucomutase-1 isoform 1. PGM1 belongs to the phosphohexose mutase family. There are several PGM isozymes, which are catalyze the transfer of phosphate between the 1 and 6 positions of glucose. In most cell types, PGM1 isozymes predominate, representing about 90 % of total PGM activity. Defects in PGM1 are the cause of glycogen storage disease type 14. Recombinant human PGM1, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques

Molecular Weight: 63.8 kDa (585aa)

NCBI Accession: NP_002624

UniProt: P36871

Pathways: Cellular Glucan Metabolic Process