ACTN1 Protein (AA 1-249) (His tag)
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- Target See all ACTN1 Proteins
- ACTN1 (Actinin, alpha 1 (ACTN1))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-249
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This ACTN1 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- MGSSHHHHHH SSGLVPRGSH MGSEFMDHYD SQQTNDYMQP EEDWDRDLLL DPAWEKQQRK TFTAWCNSHL RKAGTQIENI EEDFRDGLKL MLLLEVISGE RLAKPERGKM RVHKISNVNK ALDFIASKGV KLVSIGAEEI VDGNVKMTLG MIWTIILRFA IQDISVEETS AKEGLLLWCQ RKTAPYKNVN IQNFHISWKD GLGFCALIHR HRPELIDYGK LRKDDPLTNL NTAFDVAEKY LDIPKMLDAE DIVGTARPDE KAIMTYVSSF YHAF
- Purity
- > 95 % by SDS - PAGE
- Top Product
- Discover our top product ACTN1 Protein
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Actinin, alpha 1 (ACTN1) (AA 272-490) protein (His-IF2DI Tag)
ACTN1 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Actinin, alpha 1 (ACTN1) (AA 1-892) protein (GST tag)ACTN1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Actinin, alpha 1 (ACTN1) (AA 543-639) protein (GST tag)ACTN1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Actinin, alpha 1 (ACTN1) (AA 1-892) protein (Strep Tag)Crystallography grade ACTN1 Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
Actinin, alpha 1 (ACTN1) (AA 1-892) protein (Strep Tag)Crystallography grade ACTN1 Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
Actinin, alpha 1 (ACTN1) (Transcript Variant 2) protein (Myc-DYKDDDDK Tag)ACTN1 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Liquid. In Phosphate Buffered Saline ( pH 7.4) containing 10 % glycerol
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
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- Target
- ACTN1 (Actinin, alpha 1 (ACTN1))
- Alternative Name
- ACTN1 (ACTN1 Products)
- Synonyms
- ACTN1 Protein, actinin Protein, BDPLT15 Protein, 3110023F10Rik Protein, Actn1a Protein, actinin alpha 1 Protein, actinin, alpha 1 Protein, actinin alpha 1 L homeolog Protein, ACTN1 Protein, actn1 Protein, Actn1 Protein, actn1.L Protein
- Background
- ACTN1 also known as alpha-actinin-1 isoform a. ACTN1 functions as an actin-binding-protein. ACTN1 determines the motility of keratinocytes by regulating the organization of the actin cytoskeleton, focal adhesion, and hemidesmosome proteins complexes, thereby modulating cell speed, lamellipodial dynamics, and directed migration. Recombinant human ACTN1, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
- Molecular Weight
- 31.4kDa (274aa) confirmed by MALDI-TOF
- NCBI Accession
- NP_001123476
- UniProt
- P12814
- Pathways
- Cell-Cell Junction Organization
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