CD131 Protein (AA 17-443) (His tag)
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- Target See all CD131 (CSF2RB) Proteins
- CD131 (CSF2RB) (Colony Stimulating Factor 2 Receptor, Beta (CSF2RB))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 17-443
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Origin
- Human
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Source
- Baculovirus infected Insect Cells
- Purification tag / Conjugate
- This CD131 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- WERSLAGAEE TIPLQTLRCY NDYTSHITCR WADTQDAQRL VNVTLIRRVN EDLLEPVSCD LSDDMPWSAC PHPRCVPRRC VIPCQSFVVT DVDYFSFQPD RPLGTRLTVT LTQHVQPPEP RDLQISTDQD HFLLTWSVAL GSPQSHWLSP GDLEFEVVYK RLQDSWEDAA ILLSNTSQAT LGPEHLMPSS TYVARVRTRL APGSRLSGRP SKWSPEVCWD SQPGDEAQPQ NLECFFDGAA VLSCSWEVRK EVASSVSFGL FYKPSPDAGE EECSPVLREG LGSLHTRHHC QIPVPDPATH GQYIVSVQPR RAEKHIKSSV NIQMAPPSLN VTKDGDSYSL RWETMKMRYE HIDHTFEIQY RKDTATWKDS KTETLQNAHS MALPALEPST RYWARVRVRT SRTGYNGIWS EWSEARSWDT ESVLPMWLEH HHHHH
- Purity
- > 95 % by SDS - PAGE
- Endotoxin Level
- < 1.0 EU per 1 microgram of protein (determined by LAL method)
- Top Product
- Discover our top product CSF2RB Protein
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Colony Stimulating Factor 2 Receptor, Beta (CSF2RB) (AA 23-441) protein (His tag)
Crystallography grade CSF2RB Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Colony Stimulating Factor 2 Receptor, Beta (CSF2RB) (AA 17-443) protein (His tag)Crystallography grade CSF2RB Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Colony Stimulating Factor 2 Receptor, Beta (CSF2RB) (AA 461-897) protein (His tag)Crystallography grade CSF2RB Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Colony Stimulating Factor 2 Receptor, Beta (CSF2RB) (AA 464-896) protein (His tag)Crystallography grade CSF2RB Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Colony Stimulating Factor 2 Receptor, Beta (CSF2RB) (AA 17-897) protein (rho-1D4 tag)Crystallography grade CSF2RB Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Colony Stimulating Factor 2 Receptor, Beta (CSF2RB) (AA 23-896) protein (rho-1D4 tag)Crystallography grade CSF2RB Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 mg/mL
- Buffer
- Liquid. In Phosphate Buffered Saline ( pH 7.4) containing 10 % glycerol.
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
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- Target
- CD131 (CSF2RB) (Colony Stimulating Factor 2 Receptor, Beta (CSF2RB))
- Alternative Name
- Cytokine receptor common subunit beta (CSF2RB Products)
- Synonyms
- Csf2rb1 Protein, CSF2RB Protein, cd131 Protein, cdw131 Protein, il3rb Protein, il5rb Protein, il-3rbc Protein, CD131 Protein, CDw131 Protein, IL3RB Protein, IL5RB Protein, SMDP5 Protein, AI848964 Protein, AIC2B Protein, Bc Protein, Csfgmrb Protein, Il3r Protein, Il3rb Protein, Il3rb1 Protein, Il5rb Protein, colony stimulating factor 2 receptor beta common subunit Protein, colony stimulating factor 2 receptor beta common subunit S homeolog Protein, cytokine receptor common subunit beta-like Protein, colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) Protein, CSF2RB Protein, Csf2rb Protein, csf2rb.S Protein, CRCBL Protein, csf2rb Protein
- Background
- CSF2RB, also known as cytokine receptor common subunit beta, is a high affinity receptor for interleukin-3, interleukin-5 and granulocyte-macrophage colony-stimulating factor. This unusual form of receptor assembly likely applies also to IL-3 and IL-5 receptors, providing a structural basis for understanding their mechanism of activation and for the development of therapeutics. Recombinant human CSF2RB, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
- Molecular Weight
- 49.7kDa (435aa) 40-57kDa (SDS-PAGE under reducing conditions)
- NCBI Accession
- NP_000386
- UniProt
- P32927
- Pathways
- JAK-STAT Signaling
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