CD320 Molecule (CD320) (AA 31-229) protein (hIgG-His-tag)

Details for Product No. ABIN5854903, Supplier: Log in to see
Protein Name
  • 8D6
  • 8D6A
  • TCBLR
  • 425O18-1
  • D17Ertd716e
  • NG29
  • VLDL
  • RGD1305860
  • TCblR
  • CD320 molecule
  • CD320 antigen
  • CD320
  • Cd320
Protein Characteristics
AA 31-229
6
3
2
2
2
1
1
1
1
1
1
1
1
1
Origin
Human
25
4
2
1
Source
Baculovirus infected Insect Cells
13
6
4
3
3
2
1
Protein Type
Recombinant
Purification tag / Conjugate
This CD320 protein is labelled with hIgG-His-tag.
Application
SDS-PAGE (SDS)
Options
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Sequence LEAAASPLST PTSAQAAGPS SGSCPPTKFQ CRTSGLCVPL TWRCDRDLDC SDGSDEEECR IEPCTQKGQC PPPPGLPCPC TGVSDCSGGT DKKLRNCSRL ACLAGELRCT LSDDCIPLTW RCDGHPDCPD SSDELGCGTN EILPEGDATT MGPPVTLESV TSLRNATTMG PPVTLESVPS VGNATSSSAG DQSGSPTAYL EPKSCDKTHT CPPCPAPELL GGPSVFLFPP KPKDTLMISR TPEVTCVVVD VSHEDPEVKF NWYVDGVEVH NAKTKPREEQ YNSTYRVVSV LTVLHQDWLN GKEYKCKVSN KALPAPIEKT ISKAKGQPRE PQVYTLPPSR DELTKNQVSL TCLVKGFYPS DIAVEWESNG QPENNYKTTP PVLDSDGSFF LYSKLTVDKS RWQQGNVFSC SVMHEALHNH YTQKSLSLSP GKHHHHHH
Purity > 90 % by SDS - PAGE
Endotoxin Level < 1.0 EU per 1 microgram of protein (determined by LAL method)
Protein Name
Background CD320, also known as CD320 antigen isoform 1, belongs to the low-density lipoprotein receptor family, with 2 low-density lipoprotein receptor type A domains separated by a complement-like cysteine-rich region. It binds TC- cobalamin (Cbl) and internalizes the complex by endocytosis. It is known to enhance proliferation of germinal center (GC) B cells and follicular dendritic cells. It augments the proliferation of PC precursors generated by IL-10. It collaborates with CD44 in supporting lymphomagenesis by a Burkitt lymphoma cell line, L3055. Recombinant human CD320, fused to hIgG-His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Molecular Weight 47.4kDa (438aa) 57-70kDa (SDS-PAGE under reducing conditions)
NCBI Accession NP_057663
UniProt Q9NPF0
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer Liquid. In Phosphate Buffered Saline (  pH 7.4) containing 10 % glycerol.
Storage 4 °C,-20 °C,-80 °C
Storage Comment Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
Supplier Images
SDS-PAGE (SDS) image for CD320 Molecule (CD320) (AA 31-229) protein (hIgG-His-tag) (ABIN5854903) CD320 Molecule (CD320) (AA 31-229) protein (hIgG-His-tag)