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IL15RA Protein (AA 31-205) (hIgG-His-tag)

IL15RA Origin: Human Host: Baculovirus infected Insect Cells Recombinant > 85 % by SDS - PAGE SDS
Catalog No. ABIN7529371
  • Target See all IL15RA Proteins
    IL15RA (Interleukin 15 Receptor, alpha (IL15RA))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 31-205
    Origin
    • 16
    • 6
    • 1
    Human
    Source
    • 11
    • 4
    • 3
    • 3
    • 1
    • 1
    Baculovirus infected Insect Cells
    Purification tag / Conjugate
    This IL15RA protein is labelled with hIgG-His-tag.
    Application
    SDS-PAGE (SDS)
    Sequence
    ADPITCPPPM SVEHADIWVK SYSLYSRERY ICNSGFKRKA GTSSLTECVL NKATNVAHWT TPSLKCIRDP ALVHQRPAPP STVTTAGVTP QPESLSPSGK EPAASSPSSN NTAATTAAIV PGSQLMPSKS PSTGTTEISS HESSHGTPSQ TTAKNWELTA SASHQPPGVY PQGHSDTTLE PKSCDKTHTC PPCPAPELLG GPSVFLFPPK PKDTLMISRT PEVTCVVVDV SHEDPEVKFN WYVDGVEVHN AKTKPREEQY NSTYRVVSVL TVLHQDWLNG KEYKCKVSNK ALPAPIEKTI SKAKGQPREP QVYTLPPSRD ELTKNQVSLT CLVKGFYPSD IAVEWESNGQ PENNYKTTPP VLDSDGSFFL YSKLTVDKSR WQQGNVFSCS VMHEALHNHY TQKSLSLSPG KHHHHHH
    Purity
    > 85 % by SDS - PAGE
    Endotoxin Level
    < 1.0 EU per 1ug of protein (determined by LAL method)
    Top Product
    Discover our top product IL15RA Protein
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.5 mg/mL
    Buffer
    Liquid. In Phosphate Buffered Saline (  pH 7.4) containing 10 % glycerol.
    Storage
    4 °C,-20 °C,-80 °C
    Storage Comment
    Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
  • Target
    IL15RA (Interleukin 15 Receptor, alpha (IL15RA))
    Alternative Name
    IL15RA (IL15RA Products)
    Synonyms
    IL15RA Protein, CD215 Protein, AA690181 Protein, IL-15RA Protein, interleukin 15 receptor subunit alpha Protein, interleukin 15 receptor, alpha chain Protein, IL15RA Protein, Il15ra Protein
    Background
    IL15RA, also known as interleukin-15 receptor subunit alpha isoform 1, is a high-affinity receptor for interleukin-15. It associates as a heterotrimer with the IL-2 receptor beta and gamma subunits to initiate signal transduction. This protein can signal both in cis and trans where IL15R from one subset of cells presents IL15 to neighboring IL2RG-expressing cells. IL15/IL15R alpha complexes can transmit reverse signaling that promotes cellular adhesion, tyrosine phosphorylation of intracellular proteins, and cytokine secretion by the IL 15/IL15R alpha expressing cells. Recombinant human IL15RA protein, fused to hIgG-His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
    Molecular Weight
    45.6kDa (417aa) 57-70KDa (SDS-PAGE under reducing conditions.)
    NCBI Accession
    NP_002180
    UniProt
    Q13261
    Pathways
    JAK-STAT Signaling
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