Epiregulin Protein (EREG)
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- Target See all Epiregulin (EREG) Proteins
- Epiregulin (EREG)
- Protein Type
- Recombinant
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Origin
- Human
- Host
- Please inquire
- Sequence
- MVAQVSITKC SSDMNGYCLH GQCIYLVDMS QNYCRCEVGY TGV
- Characteristics
- Recombinant Human Epiregulin
- Purity
- > 97 % as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
- Top Product
- Discover our top product EREG Protein
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Epiregulin (EREG) (AA 56-101) protein (Fc Tag)
EREG Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Epiregulin (EREG) (AA 63-108) protein (Fc Tag)EREG Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Epiregulin (EREG) (AA 60-108) protein (His-IF2DI Tag)EREG Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Epiregulin (EREG) (AA 1-169) protein (GST tag)EREG Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Epiregulin (EREG) (AA 32-117) protein (GST tag)EREG Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Epiregulin (EREG) (AA 30-169) protein (rho-1D4 tag)Crystallography grade EREG Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Epiregulin (EREG) (AA 63-108) protein (rho-1D4 tag)Crystallography grade EREG Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Epiregulin (EREG) (AA 56-101) protein (rho-1D4 tag)Crystallography grade EREG Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Epiregulin (EREG) (AA 23-162) protein (rho-1D4 tag)Crystallography grade EREG Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- Epiregulin was lyophilized from 0.5mg/ml solution ciontaing 20mM PBS buffer pH-7.4 containing 130mM sodium chloride.It is recommended to reconstitute the lyophilized Epiregulin in sterile 18M -cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.
- Storage
- -20 °C
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- Target
- Epiregulin (EREG)
- Alternative Name
- Epiregulin (EREG Products)
- Synonyms
- EREG Protein, ER Protein, EPR Protein, proepiregulin Protein, epiregulin Protein, EREG Protein, ereg Protein, Ereg Protein
- Background
- Epiregulin Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 50 amino acids and having a molecular mass of 6 kDa. Epiregulin is purified by proprietary chromatographic techniques. Introduction: Epiregulin is part of the EGF family. Epiregulin functions as a ligand of EGFR, as well as a ligand of most members of the ERBB (v-erb-b2 oncogene homolog) family of tyrosine-kinase receptors. Epiregulin is expressed mostly in the placenta and peripheral blood leukocytes and in specific carcinomas of the bladder, lung, kidney and colon. Epiregulin stimulates the proliferation of keratinocytes, hepatocytes, fibroblasts and vascular smooth muscle cells. Epiregulin inhibits the growth of several tumor-derived epithelial cell lines. Human Epiregulin is initially synthesized as a glycosylated 19.0 kDa transmembrane precursor protein, which is processed by proteolytic cleavage to produce a 6.0 kDa mature secreted sequence. Synonyms: EREG, Epiregulin, ER.
- Pathways
- RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Muscle Cell Differentiation
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