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Interferon gamma Protein (IFNG) (AA 24-166) (His tag)

IFNG Origin: Human Host: HEK-293 Cells > 95 % CC, AcA Active
Catalog No. ABIN6239726
  • Target See all Interferon gamma (IFNG) Proteins
    Interferon gamma (IFNG)
    Biological Activity
    Active
    Protein Characteristics
    AA 24-166
    Origin
    • 26
    • 13
    • 13
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Source
    • 52
    • 34
    • 13
    • 6
    • 2
    • 2
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This Interferon gamma protein is labelled with His tag.
    Application
    Cell Culture (CC), Activity Assay (AcA)
    Characteristics
    Tag location: N-terminal His Tag
    Purity
    > 95 %
    Biological Activity Comment
    IFN-γ is a dimerized soluble cytokine that is the only member of the type II class of interferons.The importance of IFNγ in the immune system stems in part from its ability to inhibit viral replication directly, and most importantly from its immunostimulatory and immunomodulatory effects. As reported, IFNγ is an important activator of human monocytic THP1 cells. Therefore,THP-1 cells were incubated in RPMI 1640 with various concentration of IFN-γ , then cells were observed by inverted microscope everyday.After stimulated with IFN-γ(5ng/ml) for 5 days, morphological changes occured in THP1 cells which displayed the shape of fusiform or polygon and were more likely to adhere. Effect of IFN-γ on THP1 cells is shown in Figure 1.
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    Discover our top product IFNG Protein
  • Application Notes
    Isoelectric Point: 9.7
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    20 mM Tris, 150 mM NaCl, pH 8.0, containing 1 mM EDTA, 1 mM DTT, 0.01 % SKL, 5 % Trehalose and Proclin300.
    Preservative
    Dithiothreitol (DTT), Other preservative, ProClin
    Precaution of Use
    This product contains ProClin and Dithiothreitol (DTT): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
  • Target
    Interferon gamma (IFNG)
    Abstract
    IFNG Products
    Synonyms
    IFG Protein, IFI Protein, IFN-g Protein, Ifg Protein, IFNG2 Protein, IFN-gamma Protein, IFN-G Protein, IFNG Protein, IFNgamma Protein, TCRalpha Protein, INF-G Protein, ifng Protein, interferon gamma Protein, interferon, gamma 1-2 Protein, IFNG Protein, Ifng Protein, ifng1-2 Protein
    Background
    Alternative Names: IFN-G, IFG, IFI, INFr, IFN, Immune Interferon
    Molecular Weight
    22&25kDa
    UniProt
    P01579
    Pathways
    Interferon-gamma Pathway, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, ER-Nucleus Signaling, Regulation of Carbohydrate Metabolic Process, Protein targeting to Nucleus, Autophagy
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