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ISCU Protein (AA 35-167) (His tag)

ISCU Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % by SDS - PAGE SDS
Catalog No. ABIN6386664
  • Target See all ISCU Proteins
    ISCU (Iron-sulfur cluster assembly enzyme ISCU, mitochondrial (ISCU))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 35-167
    Origin
    • 3
    • 1
    • 1
    Human
    Source
    • 2
    • 1
    • 1
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This ISCU protein is labelled with His tag.
    Application
    SDS-PAGE (SDS)
    Characteristics
    ISCU, 35-167aa, Human, His tag, E.coli
    Purity
    > 90 % by SDS - PAGE
    Top Product
    Discover our top product ISCU Protein
  • Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.5mg/ml (determined by Bradford assay)
    Buffer
    Liquid. 20mM Tris-HCl buffer (pH8.0) containing 10% glycerol, 2mM DTT, 100mM NaCl
    Storage
    4 °C
  • Target
    ISCU (Iron-sulfur cluster assembly enzyme ISCU, mitochondrial (ISCU))
    Alternative Name
    ISCU (ISCU Products)
    Synonyms
    nifun Protein, zC191D15.3 Protein, si:ch211-191d15.3 Protein, 2310020H20Rik Protein, HML Protein, ISU2 Protein, NIFU Protein, NIFUN Protein, hnifU Protein, RGD1309562 Protein, AA407971 Protein, Nifu Protein, Nifun Protein, iron-sulfur cluster assembly enzyme ISCU, mitochondrial Protein, iron-sulfur cluster assembly enzyme Protein, iron-sulfur cluster assembly enzyme a Protein, LOC409130 Protein, ISCU Protein, iscua Protein, Iscu Protein
    Background
    Iron-sulfur cluster assembly enzyme, also known as ISCU, is a member of the nifU family. Iron-sulfur (Fe-S) clusters are necessary for several mitochondrial enzymes and other subcellular compartment proteins. It is interact with ISCS, a cysteine desulfurase, to sequester inorganic sulfur for Fe-S cluster assembly. ISCU-ISCS protein complex localizes in both mitochondria and cytosol, implying that Fe-S cluster assembly takes place in multiple subcellular compartments in mammalian cells. Recombinant human ISCU protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: Iron-sulfur cluster assembly enzyme ISCU, HML, hnifU, ISU2, NIFU, NIFUN. NCBI no.: NP_998760
    Molecular Weight
    16.7kDa (154aa), confirmed by MALDI-TOF
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