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PSMB10 Protein (AA 40-273) (His tag)

PSMB10 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % by SDS - PAGE SDS
Catalog No. ABIN7279563
  • Target See all PSMB10 Proteins
    PSMB10 (Proteasome (Prosome, Macropain) Subunit, beta Type 10 (PSMB10))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 40-273
    Origin
    • 3
    • 1
    • 1
    • 1
    Human
    Source
    • 3
    • 2
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This PSMB10 protein is labelled with His tag.
    Application
    SDS-PAGE (SDS)
    Characteristics
    PSMB10, 40-273aa, Human, His tag, E.coli
    Purity
    > 90 % by SDS - PAGE
    Top Product
    Discover our top product PSMB10 Protein
  • Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.25 mg/ml (determined by Bradford assay)
    Buffer
    Liquid. 20mM Tris-HCl buffer (pH8.0) containing 40% glycerol, 0.1M NaCl
    Storage
    4 °C
  • Target
    PSMB10 (Proteasome (Prosome, Macropain) Subunit, beta Type 10 (PSMB10))
    Alternative Name
    PSMB10 (PSMB10 Products)
    Synonyms
    Mecl-1 Protein, Mecl1 Protein, LMP10 Protein, MECL1 Protein, beta2i Protein, proteasome (prosome, macropain) subunit, beta type 10 Protein, proteasome subunit beta 10 Protein, Psmb10 Protein, PSMB10 Protein
    Background
    PSMB10 is a member of the proteasome B-type family, also known as the T1B family, which is a 20S core beta subunit. The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. Expression of the PSMB10 gene is induced by gamma interferon, and PSMB10 replaces catalytic subunit 2 (proteasome beta 7 subunit) in the immunoproteasome. Recombinant human PSMB10 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography. Synonyms: Proteasome subunit beta type-10, LMP10, MECL1. NCBI no.: NP_002792
    Molecular Weight
    26.9 kDa (255aa), confirmed by MALDI-TOF
    Pathways
    Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA
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