NEIL1 Protein (AA 1-390) (His tag)
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- Target See all NEIL1 Proteins
- NEIL1 (Endonuclease VIII-Like 1 (NEIL1))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-390
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This NEIL1 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Characteristics
- NEIL1, 1-390aa , Human, His tag E.coli
- Purity
- > 90 % by SDS - PAGE
- Top Product
- Discover our top product NEIL1 Protein
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 mg/ml (determined by Bradford assay)
- Buffer
- Liquid. 20mM Tris-HCl buffer (pH8.0) containing 20% glycerol, 0.1M NaCl,1mM DTT, 0.1mM PMSF
- Storage
- 4 °C
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- Target
- NEIL1 (Endonuclease VIII-Like 1 (NEIL1))
- Alternative Name
- NEIL1 (NEIL1 Products)
- Synonyms
- FPG1 Protein, NEI1 Protein, hFPG1 Protein, 2810450N13Rik Protein, Nei1 Protein, nei-like DNA glycosylase 1 Protein, nei like DNA glycosylase 1 Protein, nei endonuclease VIII-like 1 (E. coli) Protein, Neil1 Protein, NEIL1 Protein
- Background
- NEIL1 belongs to a class of DNA glycosylases homologous to the bacterial Fpg/Nei family. These glycosylases initiate the first step in base excision repair by cleaving bases damaged by reactive oxygen species and introducing a DNA strand break via the associated lyase reaction. Recombinant human NEIL1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography. Synonyms: Endonuclease 8-like 1, FLJ22402, FPG1, hFPG1, NEI1. NCBI no.: NP_078884
- Molecular Weight
- 45.8 kDa (410aa), confirmed by MALDI-TOF
- Pathways
- DNA Damage Repair
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