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NEIL1 Protein (AA 1-390) (His tag)

NEIL1 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % by SDS - PAGE SDS
Catalog No. ABIN7279660
  • Target See all NEIL1 Proteins
    NEIL1 (Endonuclease VIII-Like 1 (NEIL1))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 1-390
    Origin
    • 9
    • 1
    Human
    Source
    • 5
    • 2
    • 2
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This NEIL1 protein is labelled with His tag.
    Application
    SDS-PAGE (SDS)
    Characteristics
    NEIL1, 1-390aa , Human, His tag E.coli
    Purity
    > 90 % by SDS - PAGE
    Top Product
    Discover our top product NEIL1 Protein
  • Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.5 mg/ml (determined by Bradford assay)
    Buffer
    Liquid. 20mM Tris-HCl buffer (pH8.0) containing 20% glycerol, 0.1M NaCl,1mM DTT, 0.1mM PMSF
    Storage
    4 °C
  • Target
    NEIL1 (Endonuclease VIII-Like 1 (NEIL1))
    Alternative Name
    NEIL1 (NEIL1 Products)
    Synonyms
    FPG1 Protein, NEI1 Protein, hFPG1 Protein, 2810450N13Rik Protein, Nei1 Protein, nei-like DNA glycosylase 1 Protein, nei like DNA glycosylase 1 Protein, nei endonuclease VIII-like 1 (E. coli) Protein, Neil1 Protein, NEIL1 Protein
    Background
    NEIL1 belongs to a class of DNA glycosylases homologous to the bacterial Fpg/Nei family. These glycosylases initiate the first step in base excision repair by cleaving bases damaged by reactive oxygen species and introducing a DNA strand break via the associated lyase reaction. Recombinant human NEIL1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography. Synonyms: Endonuclease 8-like 1, FLJ22402, FPG1, hFPG1, NEI1. NCBI no.: NP_078884
    Molecular Weight
    45.8 kDa (410aa), confirmed by MALDI-TOF
    Pathways
    DNA Damage Repair
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