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RGS14 Protein (His tag)

RGS14 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 80 % by SDS - PAGE SDS
Catalog No. ABIN6386992
  • Target See all RGS14 Proteins
    RGS14 (Regulator of G-Protein Signaling 14 (RGS14))
    Protein Type
    Recombinant
    Origin
    • 5
    • 1
    • 1
    Human
    Source
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This RGS14 protein is labelled with His tag.
    Application
    SDS-PAGE (SDS)
    Purification
    purified by chromatography
    Purity
    > 80 % by SDS - PAGE
    Top Product
    Discover our top product RGS14 Protein
  • Comment

    Synonyms: regulator of G-protein signaling 14

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.5 mg/ml (determined by Bradford assay)
    Buffer
    20 mM Tris-HCl buffer, pH7.5, 10% glycerol, 1 MM DTT, 200 mM NaCl
    Storage
    4 °C
    Storage Comment
    Avoid repeated freezing and thawing cycles.
  • Target
    RGS14 (Regulator of G-Protein Signaling 14 (RGS14))
    Alternative Name
    RGS14 (RGS14 Products)
    Synonyms
    RPIP1 Protein, MGC80558 Protein, RGS14 Protein, rgs14 Protein, wu:fi04g12 Protein, regulator of G protein signaling 14 Protein, regulator of G-protein signaling 14 Protein, regulator of G-protein signaling 14 L homeolog Protein, regulator of G-protein signalling 14 Protein, regulator of G protein signaling 14a Protein, RGS14 Protein, Rgs14 Protein, rgs14.L Protein, rgs14 Protein, rgs14a Protein
    Background
    RGS14 (Regulator of G-protein signaling 14) belongs to regulator of G protein signalling family. This protein contains one RGS domain, two Raf-like Ras-binding domains (RBDs), and one GoLoco motif. RGS14 is highly enriched in CA2 pyramidal neurons and plays a role in suppression of both synaptic plasticity at these synapses and hippocampal-based learning and memory. RGS14 is a scaffolding protein that integrates G protein and H-Ras/ERK/MAP kinase signaling pathways, thereby making it well positioned to suppress plasticity in CA2 neurons. Recombinant human RGS14 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
    Molecular Weight
    63.6kDa (586aa)
    NCBI Accession
    NP_006471
    Pathways
    Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling, Platelet-derived growth Factor Receptor Signaling
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