RGS14 Protein (His tag)
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- Target See all RGS14 Proteins
- RGS14 (Regulator of G-Protein Signaling 14 (RGS14))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This RGS14 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Purification
- purified by chromatography
- Purity
- > 80 % by SDS - PAGE
- Top Product
- Discover our top product RGS14 Protein
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- Comment
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Synonyms: regulator of G-protein signaling 14
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 mg/ml (determined by Bradford assay)
- Buffer
- 20 mM Tris-HCl buffer, pH7.5, 10% glycerol, 1 MM DTT, 200 mM NaCl
- Storage
- 4 °C
- Storage Comment
- Avoid repeated freezing and thawing cycles.
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- Target
- RGS14 (Regulator of G-Protein Signaling 14 (RGS14))
- Alternative Name
- RGS14 (RGS14 Products)
- Synonyms
- RPIP1 Protein, MGC80558 Protein, RGS14 Protein, rgs14 Protein, wu:fi04g12 Protein, regulator of G protein signaling 14 Protein, regulator of G-protein signaling 14 Protein, regulator of G-protein signaling 14 L homeolog Protein, regulator of G-protein signalling 14 Protein, regulator of G protein signaling 14a Protein, RGS14 Protein, Rgs14 Protein, rgs14.L Protein, rgs14 Protein, rgs14a Protein
- Background
- RGS14 (Regulator of G-protein signaling 14) belongs to regulator of G protein signalling family. This protein contains one RGS domain, two Raf-like Ras-binding domains (RBDs), and one GoLoco motif. RGS14 is highly enriched in CA2 pyramidal neurons and plays a role in suppression of both synaptic plasticity at these synapses and hippocampal-based learning and memory. RGS14 is a scaffolding protein that integrates G protein and H-Ras/ERK/MAP kinase signaling pathways, thereby making it well positioned to suppress plasticity in CA2 neurons. Recombinant human RGS14 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
- Molecular Weight
- 63.6kDa (586aa)
- NCBI Accession
- NP_006471
- Pathways
- Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling, Platelet-derived growth Factor Receptor Signaling
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