TBCC Protein (His tag)
-
- Target See all TBCC Proteins
- TBCC (Tubulin Folding Cofactor C (TBCC))
- Protein Type
- Recombinant
-
Origin
- Human
-
Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This TBCC protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Purification
- purified by chromatography
- Purity
- > 85 % by SDS - PAGE
- Top Product
- Discover our top product TBCC Protein
-
Tubulin Folding Cofactor C (TBCC) (AA 1-346) protein (GST tag)
TBCC Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
Tubulin Folding Cofactor C (TBCC) (AA 1-346) protein (Strep Tag)Crystallography grade TBCC Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, ELISA, WB
Tubulin Folding Cofactor C (TBCC) (AA 1-341) protein (Strep Tag)Crystallography grade TBCC Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, ELISA, WB
Tubulin Folding Cofactor C (TBCC) (AA 2-345) protein (His tag)TBCC Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % SDS
Tubulin Folding Cofactor C (TBCC) protein (Myc-DYKDDDDK Tag)TBCC Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
-
- Comment
-
Synonyms: Tubulin-specific chaperone C, CFC, tubulin folding cofactor C
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- 0.5 mg/ml (determined by Bradford assay)
- Buffer
- 20 mM Tris-HCl buffer (pH 8.0) containing 0.1 M NaCl, 10% glycerol,1 MM DTT
- Storage
- 4 °C
- Storage Comment
- Avoid repeated freezing and thawing cycles.
-
- Target
- TBCC (Tubulin Folding Cofactor C (TBCC))
- Alternative Name
- TBCC (TBCC Products)
- Synonyms
- CFC Protein, 2810055C19Rik Protein, tubulin folding cofactor C Protein, tubulin-specific chaperone C Protein, TBCC Protein, Tbcc Protein
- Background
- TBCC (tubulin folding cofactor C) belongs to the TBCC family. It is plays a role in the regulation of centrosome and Golgi apparatus positioning, with consequences on cell shape and cell migration. Cofactor C is one of four proteins(cofactors A,D,E and C) involved in the pathway leading to correctly folded b-tubulin from folding intermediates. Cofactors A and D are believed to play a role in capturing and stabilizing b-tubulin intermediates in a quasi-native confirmation. Cofactor E binds to the cofactor D/b-tubulin complex, interaction with cofactor C then causes the release of b-tubulin polypeptides. Recombinant human TBCC protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
- Molecular Weight
- 41.7 kDa (369aa), confirmed by MALDI-TOF
- NCBI Accession
- NP_003183
-
