PARD6B Protein (His tag)
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- Target See all PARD6B Proteins
- PARD6B (Par-6 Partitioning Defective 6 Homolog beta (PARD6B))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This PARD6B protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Purity
- > 85 % by SDS - PAGE
- Top Product
- Discover our top product PARD6B Protein
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Par-6 Partitioning Defective 6 Homolog beta (PARD6B) (AA 1-372) protein (GST tag)
PARD6B Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
Par-6 Partitioning Defective 6 Homolog beta (PARD6B) (AA 1-372) protein (Strep Tag)Crystallography grade PARD6B Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, ELISA, WB
Par-6 Partitioning Defective 6 Homolog beta (PARD6B) (AA 1-371) protein (Strep Tag)Crystallography grade PARD6B Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, ELISA, WB
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- Comment
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Synonyms: Partitioning defective 6 homolog beta, PAR6B
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 mg/ml (determined by Bradford assay)
- Buffer
- 20 mM Tris-HCl buffer (pH 8.0) containing 2 M Urea, 20% glycerol, 0.2 M NaCl
- Storage
- 4 °C
- Storage Comment
- Avoid repeated freezing and thawing cycles.
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- Target
- PARD6B (Par-6 Partitioning Defective 6 Homolog beta (PARD6B))
- Alternative Name
- PARD6B (PARD6B Products)
- Synonyms
- PARD6B Protein, AV025615 Protein, Par6b Protein, PAR6B Protein, par-6 Protein, par6 Protein, pard6beta Protein, si:dkey-192i18.6 Protein, PAR-6 Protein, PAR-6B Protein, par-6 family cell polarity regulator beta Protein, par-6 family cell polarity regulator beta S homeolog Protein, par-6 partitioning defective 6 homolog beta (C. elegans) Protein, PARD6B Protein, Pard6b Protein, pard6b.S Protein, pard6b Protein
- Background
- Partitioning defective 6 homolog beta, also known as PARD6B, is a member of the PAR6 family and encodes a protein with a PSD95/Discs-large/ZO1 (PDZ) domain, an OPR domain and a semi-Cdc42/Rac interactive binding (CRIB) domain. Cellular asymmetry is critical for the development of multicellular organisms. PARD (partitioning-defective) proteins play important roles in asymmetric cell division and polarized growth, whereas Cdc42 and Rac mediate establishment of cell growth and polarity and contribute to oncogenic transformation by Ras. It is expressed in pancreas and in both adult and fetal kidney, and is weakly expressed in placenta and lung. Recombinant human PARD6B protein, fused to His-tag at N-terminus, was expressed in E.coli.
- Molecular Weight
- 43.6 kDa (395aa)
- NCBI Accession
- NP_115910
- Pathways
- Cell-Cell Junction Organization
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