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BCL7A Protein (His tag)

BCL7A Origin: Human Host: Escherichia coli (E. coli) Recombinant > 85 % by SDS - PAGE SDS
Catalog No. ABIN6387092
  • Target See all BCL7A Proteins
    BCL7A (B-Cell CLL/lymphoma 7A (BCL7A))
    Protein Type
    Recombinant
    Origin
    • 4
    • 1
    • 1
    Human
    Source
    • 2
    • 2
    • 1
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This BCL7A protein is labelled with His tag.
    Application
    SDS-PAGE (SDS)
    Purification
    purified by chromatography
    Purity
    > 85 % by SDS - PAGE
    Top Product
    Discover our top product BCL7A Protein
  • Comment

    Synonyms: B-cell CLL/lymphoma 7 protein family member A, BCL7

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.25 mg/ml (determined by Bradford assay)
    Buffer
    20 mM Tris-HCl buffer (pH 8.0) containing 0.15 M NaCl, 10% glycerol, 1 MM DTT, 2 mM EDTA
    Storage
    4 °C
    Storage Comment
    Avoid repeated freezing and thawing cycles.
  • Target
    BCL7A (B-Cell CLL/lymphoma 7A (BCL7A))
    Alternative Name
    BCL7A (BCL7A Products)
    Synonyms
    BCL7 Protein, cb585 Protein, id:ibd1097 Protein, sb:cb585 Protein, wu:fk02d01 Protein, zgc:92023 Protein, 4432415N06Rik Protein, AI448316 Protein, bcl7a Protein, MGC89576 Protein, BCL7A Protein, BCL tumor suppressor 7A Protein, B-cell CLL/lymphoma 7A Protein, B cell CLL/lymphoma 7A Protein, B-cell CLL/lymphoma 7A L homeolog Protein, BCL7A Protein, bcl7a Protein, Bcl7a Protein, bcl7a.L Protein
    Background
    BCL7A is directly involved, with Myc and IgH, in a three-way gene translocation in a Burkitt lymphoma cell line. As a result of the gene translocation, the N-terminal region of the gene is disrupted, which is thought to be related to the pathogenesis of a subset of high-grade B cell non-Hodgkin lymphoma. The N-terminal segment involved in the translocation includes the region that shares a strong sequence similarity with those of BCL7B and BCL7C. Two transcript variants encoding different isoforms have been found for this gene. Recombinant human BCL7A protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
    Molecular Weight
    25.2 kDa (233aa), confirmed by MALDI-TOF (Molecular size on SDS-PAGE will appear higher)
    NCBI Accession
    NP_001019979
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