BEX1 Protein (AA 1-125) (His tag)
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- Target See all BEX1 Proteins
- BEX1 (Brain Expressed, X-Linked 1 (BEX1))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-125
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This BEX1 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- MGSSHHHHHH SSGLVPRGSH MGSMESKEKR AVNSLSMENA NQENEEKEQV ANKGEPLALP LDAGEYCVPR GNRRRFRVRQ PILQYRWDMM HRLGEPQARM REENMERIGE EVRQLMEKLR EKQLSHSLRA VSTDPPHHDH HDEFCLMP
- Purity
- > 80 % by SDS - PAGE
- Top Product
- Discover our top product BEX1 Protein
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Brain Expressed, X-Linked 1 (BEX1) (AA 1-125) protein (His tag)
BEX1 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE ELISA, WB
Brain Expressed, X-Linked 1 (BEX1) (AA 1-128) protein (Strep Tag)Crystallography grade BEX1 Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, SDS, WB
Brain Expressed, X-Linked 1 (BEX1) protein (Myc-DYKDDDDK Tag)BEX1 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.25 mg/mL
- Buffer
- Liquid. In 20 mM Tris-HCl buffer ( pH 8.0) containing 0.15M NaCl, 30 % glycerol
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
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- Target
- BEX1 (Brain Expressed, X-Linked 1 (BEX1))
- Alternative Name
- BEX1 (BEX1 Products)
- Synonyms
- BEX1 Protein, AA407839 Protein, AU018692 Protein, Bex4 Protein, Rex3 Protein, BEX2 Protein, HBEX2 Protein, HGR74-h Protein, brain expressed X-linked 1 Protein, brain expressed X-linked 2 Protein, brain expressed, X-linked 1 Protein, BEX1 Protein, Bex1 Protein, BEX2 Protein
- Background
- Brain expressed, X-linked 1, also known as BEX1, is signaling adapter molecule involved in p75NTR/NGFR signaling. This protein plays a role in cell cycle progression and neuronal differentiation. This protein inhibits neuronal differentiation in response to nerve growth factor (NGF). It may act as a link between the cell cycle and neurotrophic factor signaling, possibly by functioning as an upstream modulator of receptor signaling, coordinating biological responses to external signals with internal cellular states. Recombinant human BEX1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
- Molecular Weight
- 17.2 kDa (148aa), confirmed by MALDI-TOF
- NCBI Accession
- NP_060946
- UniProt
- Q9HBH7
- Pathways
- Neurotrophin Signaling Pathway
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