BSND Protein (AA 54-320) (His tag)
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- Target See all BSND Proteins
- BSND (Bartter Syndrome, Infantile, with Sensorineural Deafness (Barttin) (BSND))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 54-320
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This BSND protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- MGSSHHHHHH SSGLVPRGSH MGSCQCYPKI TFVPADSDFQ GILSPKAMGL LENGLAAEMK SPSPQPPYVR LWEEAAYDQS LPDFSHIQMK VMSYSEDHRS LLAPEMGQPK LGTSDGGEGG PGDVQAWMEA AVVIHKGSDE SEGERRLTQS WPGPLACPQG PAPLASFQDD LDMDSSEGSS PNASPHDREE ACSPQQEPQG CRCPLDRFQD FALIDAPTLE DEPQEGQQWE IALPNNWQRY PRTKVEEKEA SDTGGEEPEK EEEDLYYGLP DGAGDLLPDK ELGFEPDTQG
- Purity
- > 90 % by SDS - PAGE
- Top Product
- Discover our top product BSND Protein
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Bartter Syndrome, Infantile, with Sensorineural Deafness (Barttin) (BSND) (AA 54-320) protein (His tag)
BSND Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE ELISA, WB
Bartter Syndrome, Infantile, with Sensorineural Deafness (Barttin) (BSND) (AA 221-320) protein (GST tag)BSND Origin: Human Host: Wheat germ Recombinant ELISA, WB, AA, AP
Bartter Syndrome, Infantile, with Sensorineural Deafness (Barttin) (BSND) (AA 54-320) protein (His tag)Crystallography grade BSND Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, ELISA, WB, Crys
Bartter Syndrome, Infantile, with Sensorineural Deafness (Barttin) (BSND) (AA 54-307) protein (His tag)Crystallography grade BSND Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, ELISA, WB, Crys
Bartter Syndrome, Infantile, with Sensorineural Deafness (Barttin) (BSND) (AA 1-320) protein (Strep Tag)Crystallography grade BSND Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, ELISA, WB
Bartter Syndrome, Infantile, with Sensorineural Deafness (Barttin) (BSND) (AA 1-307) protein (Strep Tag)Crystallography grade BSND Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, ELISA, WB
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.25 mg/mL
- Buffer
- Liquid. In 20 mM Tris-HCl buffer ( pH 8.0) containing 0.15M NaCl, 10 % glycerol, 1 mM DTT
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
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- Target
- BSND (Bartter Syndrome, Infantile, with Sensorineural Deafness (Barttin) (BSND))
- Alternative Name
- BSND (BSND Products)
- Synonyms
- BSND Protein, BART Protein, DFNB73 Protein, Bartter syndrome, infantile, with sensorineural deafness (Barttin) Protein, barttin CLCNK type accessory beta subunit Protein, BSND Protein, Bsnd Protein
- Background
- BSND is an essential beta subunit for CLC chloride channels. These heteromeric channels localize to basolateral membranes of renal tubules and of potassium-secreting epithelia of the inner ear. Mutations in this BSND have been associated with Bartter syndrome with sensorineural deafness. Recombinant human BSND protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
- Molecular Weight
- 31.7 kDa (290aa) confirmed by MALDI-TOF
- NCBI Accession
- NP_476517
- UniProt
- Q8WZ55
- Pathways
- Sensory Perception of Sound
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