TSHB Protein (AA 21-138) (His tag)
-
- Target See all TSHB Proteins
- TSHB (Thyroid Stimulating Hormone, beta (TSHB))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 21-138
-
Origin
- Human
-
Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This TSHB protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- MGSSHHHHHH SSGLVPRGSH MGSFCIPTEY TMHIERRECA YCLTINTTIC AGYCMTRDIN GKLFLPKYAL SQDVCTYRDF IYRTVEIPGC PLHVAPYFSY PVALSCKCGK CNTDYSDCIH EAIKTNYCTK PQKSYLVGFS V
- Purity
- > 85 % by SDS - PAGE
- Top Product
- Discover our top product TSHB Protein
-
-
- Application Notes
- Optimal working dilution should be determined by the investigator.
- Comment
-
Denatured
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- 0.25 mg/mL
- Buffer
- Liquid. In 20 mM Tris-HCl buffer ( pH 8.5) containing 10 % glycerol, 0.4M Urea
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
-
- Target
- TSHB (Thyroid Stimulating Hormone, beta (TSHB))
- Alternative Name
- TSHB (TSHB Products)
- Synonyms
- TSH-B Protein, TSH-BETA Protein, TSHB Protein, thyroid stimulating hormone beta Protein, thyroid stimulating hormone, beta Protein, thyroid stimulating hormone, beta subunit Protein, TSHB Protein, Tshb Protein, tshb Protein
- Background
- The four human glycoprotein hormones chorionic gonadotropin (CG), luteinizing hormone (LH), follicle stimulating hormone (FSH), and thyroid stimulating hormone (TSH) are dimmers consisting of alpha and beta subunits that are associated noncovalently. The alpha subunits of these hormones are identical, however, their beta chains are unique and confer biological specificity. Thyroid stimulating hormone functions in the control of thyroid structure and metabolism. TSHB is the beta subunit of thyroid stimulating hormone. Mutations in this gene result in congenital hypothyroidism. Recombinant human TSHB protein, fused to His-tag at N-terminus, was expressed in E.coli
- Molecular Weight
- 15.9kDa (141aa)
- NCBI Accession
- NP_000540
- UniProt
- P01222
- Pathways
- Thyroid Hormone Synthesis, Peptide Hormone Metabolism
-