CADM1 Protein (AA 45-374) (His tag)
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- Target See all CADM1 Proteins
- CADM1 (Cell Adhesion Molecule 1 (CADM1))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 45-374
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This CADM1 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- MGSSHHHHHH SSGLVPRGSH MGSQNLFTKD VTVIEGEVAT ISCQVNKSDD SVIQLLNPNR QTIYFRDFRP LKDSRFQLLN FSSSELKVSL TNVSISDEGR YFCQLYTDPP QESYTTITVL VPPRNLMIDI QKDTAVEGEE IEVNCTAMAS KPATTIRWFK GNTELKGKSE VEEWSDMYTV TSQLMLKVHK EDDGVPVICQ VEHPAVTGNL QTQRYLEVQY KPQVHIQMTY PLQGLTREGD ALELTCEAIG KPQPVMVTWV RVDDEMPQHA VLSGPNLFIN NLNKTDNGTY RCEASNIVGK AHSDYMLYVY DPPTTIPPPT TTTTTTTTTT TTILTIITDS RAGEEGSIRA VDH
- Purity
- > 85 % by SDS - PAGE
- Top Product
- Discover our top product CADM1 Protein
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Cell Adhesion Molecule 1 (CADM1) (AA 45-374) protein (His tag)
CADM1 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Cell Adhesion Molecule 1 (CADM1) (AA 48-388) protein (His tag)CADM1 Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Cell Adhesion Molecule 1 (CADM1) (AA 151-250) protein (GST tag)CADM1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Cell Adhesion Molecule 1 (CADM1) (Active) protein (Fc Tag)CADM1 Origin: Mouse Host: Human Cells Recombinant > 90 % as determined by SDS-PAGE Active
Cell Adhesion Molecule 1 (CADM1) (AA 1-377) protein (His tag)CADM1 Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE
Cell Adhesion Molecule 1 (CADM1) (AA 45-374) protein (His tag)Crystallography grade CADM1 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Cell Adhesion Molecule 1 (CADM1) (AA 48-388) protein (His tag)Crystallography grade CADM1 Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Cell Adhesion Molecule 1 (CADM1) (AA 45-442) protein (rho-1D4 tag)Crystallography grade CADM1 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Cell Adhesion Molecule 1 (CADM1) (AA 48-456) protein (rho-1D4 tag)Crystallography grade CADM1 Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.25 mg/mL
- Buffer
- Liquid. In Phosphate buffered saline ( pH 7.4) containing 10 % glycerol, 1 mM DTT
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
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- Target
- CADM1 (Cell Adhesion Molecule 1 (CADM1))
- Alternative Name
- CADM1 (CADM1 Products)
- Synonyms
- BL2 Protein, IGSF4 Protein, IGSF4A Protein, NECL2 Protein, Necl-2 Protein, RA175 Protein, ST17 Protein, SYNCAM Protein, TSLC1 Protein, sTSLC-1 Protein, sgIGSF Protein, synCAM1 Protein, bl2 Protein, igsf4 Protein, igsf4a Protein, necl-2 Protein, necl2 Protein, ra175 Protein, sgigsf Protein, st17 Protein, stslc-1 Protein, syncam Protein, syncam1 Protein, tslc1 Protein, xnecl2 Protein, 2900073G06Rik Protein, 3100001I08Rik Protein, AI987920 Protein, Bl2 Protein, Igsf4 Protein, Igsf4a Protein, Necl2 Protein, RA175A Protein, RA175B Protein, RA175C Protein, RA175N Protein, SgIGSF Protein, SynCam Protein, Tslc1 Protein, SynCAM1 Protein, cell adhesion molecule 1 Protein, cell adhesion molecule 1 L homeolog Protein, CADM1 Protein, cadm1.L Protein, Cadm1 Protein
- Background
- CADM1 mediates homophilic cell-cell adhesion in a Ca2+-independent manner and also mediates heterophilic cell-cell adhesion with CADM3 and PVRL3 in a Ca2+-independent manner. This protein acts as a tumor suppressor in non-small-cell lung cancer (NSCLC) cells. Interaction with CRTAM promotes natural killer (NK) cell cytotoxicity and interferon-gamma (IFN-gamma) secretion by CD8+ cells in vitro as well as NK cell-mediated rejection of tumors expressing CADM3 in vivo. Recombinant human CADM1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
- Molecular Weight
- 39.4 kDa (353aa) confirmed by MALDI-TOF
- NCBI Accession
- NP_055148
- UniProt
- Q9BY67
- Pathways
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cell-Cell Junction Organization, Activated T Cell Proliferation
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