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GZMH Protein (AA 20-246) (His tag)

GZMH Origin: Human Host: Escherichia coli (E. coli) Recombinant > 85 % by SDS - PAGE SDS
Catalog No. ABIN6387571
  • Target See all GZMH Proteins
    GZMH (Granzyme H (Cathepsin G-Like 2, Protein H-CCPX) (GZMH))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 20-246
    Origin
    Human
    Source
    • 3
    • 1
    • 1
    • 1
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This GZMH protein is labelled with His tag.
    Application
    SDS-PAGE (SDS)
    Sequence
    MGSSHHHHHH SSGLVPRGSH MEIIGGHEAK PHSRPYMAFV QFLQEKSRKR CGGILVRKDF VLTAAHCQGS SINVTLGAHN IKEQERTQQF IPVKRPIPHP AYNPKNFSND IMLLQLERKA KWTTAVRPLR LPSSKAQVKP GQLCSVAGWG YVSMSTLATT LQEVLLTVQK DCQCERLFHG NYSRATEICV GDPKKTQTGF KGDSGGPLVC KDVAQGILSY GNKKGTPPGV YIKVSHFLPW IKRTMKRL
    Purity
    > 85 % by SDS - PAGE
    Top Product
    Discover our top product GZMH Protein
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Comment

    Denatured

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.25 mg/mL
    Buffer
    Liquid. In 20  mM Tris 8.0 containing 10 % glycerol
    Storage
    4 °C,-20 °C,-80 °C
    Storage Comment
    Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
  • Target
    GZMH (Granzyme H (Cathepsin G-Like 2, Protein H-CCPX) (GZMH))
    Alternative Name
    GZMH (GZMH Products)
    Synonyms
    GZMH Protein, CCP-X Protein, CGL-2 Protein, CSP-C Protein, CTLA1 Protein, CTSGL2 Protein, granzyme H Protein, LOC617313 Protein, GZMH Protein
    Background
    GZMH also known as Granzyme H is essential for HBV eradication. The HBx protein (HBx), required for the replication of HBV, is cleaved at Met(79) by GZMH. GZMH inhibitor can abolish GZNH- and lymphokine-activated killer cell-mediated HBx degradation and HBV clearance. An HBx-deficient HBV is resistant to GzmH- and lymphokine-activated killer cell-mediated viral clearance. Recombinant human GZMH, fused to His-tag at N-terminus, was expressed in E.coli.
    Molecular Weight
    27.5kDa (248aa)
    NCBI Accession
    NP_219491
    UniProt
    P20718
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