HMGCS1 Protein (AA 1-520) (His tag)
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- Target See all HMGCS1 Proteins
- HMGCS1 (3-Hydroxy-3-Methylglutaryl-CoA Synthase 1 (Soluble) (HMGCS1))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-520
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This HMGCS1 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- MGSSHHHHHH SSGLVPRGSH MGSMPGSLPL NAEACWPKDV GIVALEIYFP SQYVDQAELE KYDGVDAGKY TIGLGQAKMG FCTDREDINS LCMTVVQNLM ERNNLSYDCI GRLEVGTETI IDKSKSVKTN LMQLFEESGN TDIEGIDTTN ACYGGTAAVF NAVNWIESSS WDGRYALVVA GDIAVYATGN ARPTGGVGAV ALLIGPNAPL IFERGLRGTH MQHAYDFYKP DMLSEYPIVD GKLSIQCYLS ALDRCYSVYC KKIHAQWQKE GNDKDFTLND FGFMIFHSPY CKLVQKSLAR MLLNDFLNDQ NRDKNSIYSG LEAFGDVKLE DTYFDRDVEK AFMKASSELF SQKTKASLLV SNQNGNMYTS SVYGSLASVL AQYSPQQLAG KRIGVFSYGS GLAATLYSLK VTQDATPGSA LDKITASLCD LKSRLDSRTG VAPDVFAENM KLREDTHHLV NYIPQGSIDS LFEGTWYLVR VDEKHRRTYA RRPTPNDDTL DEGVGLVHSN IATEHIPSPA KKVPRLPATA AEPEAAVISN GEH
- Purity
- > 80 % by SDS - PAGE
- Top Product
- Discover our top product HMGCS1 Protein
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3-Hydroxy-3-Methylglutaryl-CoA Synthase 1 (Soluble) (HMGCS1) (AA 422-520) protein (GST tag)
HMGCS1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
3-Hydroxy-3-Methylglutaryl-CoA Synthase 1 (Soluble) (HMGCS1) (AA 1-520) protein (His tag)HMGCS1 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
3-Hydroxy-3-Methylglutaryl-CoA Synthase 1 (Soluble) (HMGCS1) (AA 1-520) protein (Strep Tag)Crystallography grade HMGCS1 Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
3-Hydroxy-3-Methylglutaryl-CoA Synthase 1 (Soluble) (HMGCS1) (AA 1-520) protein (Strep Tag)Crystallography grade HMGCS1 Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
3-Hydroxy-3-Methylglutaryl-CoA Synthase 1 (Soluble) (HMGCS1) (Transcript Variant 2) protein (Myc-DYKDDDDK Tag)HMGCS1 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
3-Hydroxy-3-Methylglutaryl-CoA Synthase 1 (Soluble) (HMGCS1) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)HMGCS1 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 mg/mL
- Buffer
- Liquid. In Phosphate buffered saline ( pH 7.4) containing 10 % glycerol, 1 mM DTT
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
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- Target
- HMGCS1 (3-Hydroxy-3-Methylglutaryl-CoA Synthase 1 (Soluble) (HMGCS1))
- Alternative Name
- HMGCS1 (HMGCS1 Products)
- Synonyms
- HMGCS Protein, zgc:56481 Protein, B130032C06Rik Protein, 3-hydroxy-3-methylglutaryl-CoA synthase 1 Protein, 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) Protein, 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 1 Protein, 3-hydroxy-3-methylglutaryl coenzyme A synthase Protein, hydroxymethylglutaryl-CoA synthase Protein, 3-hydroxy-3-methylglutaryl-CoA synthase Protein, hydroxymethylglutaryl coenzyme A synthase Protein, 3-hydroxy-3-methylglutaryl-CoA synthase 1 S homeolog Protein, HMGCS1 Protein, hmgcs1 Protein, Hmgcs1 Protein, mvaS Protein, SAS2432 Protein, SZO_RS04705 Protein, SEQ_1109 Protein, NAEGRDRAFT_77778 Protein, hmgcs1.S Protein
- Background
- HMGCS1 also known as hydroxymethylglutaryl-CoA synthase, cytoplasmic. This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. Recombinant human HMGCS1 was expressed in E.coli and purified by using conventional chromatography techniques
- Molecular Weight
- 59.7kDa (543aa)
- NCBI Accession
- NP_001091742
- UniProt
- Q01581
- Pathways
- Regulation of Lipid Metabolism by PPARalpha
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