Peroxiredoxin 1 Protein (PRDX1) (AA 1-199) (His tag)
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- Target See all Peroxiredoxin 1 (PRDX1) Proteins
- Peroxiredoxin 1 (PRDX1)
- Protein Type
- Recombinant
- Biological Activity
- Active
- Protein Characteristics
- AA 1-199
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Origin
- Mouse
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Source
- Baculovirus infected Insect Cells
- Purification tag / Conjugate
- This Peroxiredoxin 1 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- MSSGNAKIGY PAPNFKATAV MPDGQFKDIS LSEYKGKYVV FFFYPLDFTF VCPTEIIAFS DRADEFKKLN CQVIGASVDS HFCHLAWINT PKKQGGLGPM NIPLISDPKR TIAQDYGVLK ADEGISFRGL FIIDDKGILR QITINDLPVG RSVDEIIRLV QAFQFTDKHG EVCPAGWKPG SDTIKPDVNK SKEYFSKQKL EHHHHHH
- Purity
- > 90 % by SDS - PAGE
- Endotoxin Level
- < 1.0 EU per 1 microgram of protein (determined by LAL method)
- Biological Activity Comment
- Specific activity is >2,500 pmol/min/ug. Enzymatic activity is defined as the amount of hydroperoxide that 1ug of enzyme can reduce at 25C for minute.
- Top Product
- Discover our top product PRDX1 Protein
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Peroxiredoxin 1 (PRDX1) (AA 1-199) (Active) protein (His tag)
PRDX1 Origin: Human Host: Escherichia coli (E. coli) Recombinant SDS, Func Active
Peroxiredoxin 1 (PRDX1) (AA 1-199) protein (GST tag)PRDX1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Peroxiredoxin 1 (PRDX1) protein (His tag)PRDX1 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant > 85 % as determined by SDS-PAGE
Peroxiredoxin 1 (PRDX1) (AA 2-199) protein (His tag)Crystallography grade PRDX1 Origin: Human Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Peroxiredoxin 1 (PRDX1) (AA 2-199) protein (His tag)Crystallography grade PRDX1 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Comment
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Bioactivity Validated
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 mg/mL
- Buffer
- Liquid. In Phosphate Buffered Saline ( pH 7.4) containing 10 % glycerol.
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
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- Target
- Peroxiredoxin 1 (PRDX1)
- Alternative Name
- Prdx1 (PRDX1 Products)
- Synonyms
- MSP23 Protein, NKEF-A Protein, NKEFA Protein, PAG Protein, PAGA Protein, PAGB Protein, PRX1 Protein, PRXI Protein, TDPX2 Protein, NkefA Protein, OSF-3 Protein, OSF3 Protein, Paga Protein, PrdxI Protein, PrxI Protein, TDX2 Protein, TPxA Protein, Tdpx2 Protein, prx1 Protein, Hbp23 Protein, MGC80194 Protein, MGC84820 Protein, PRDX1 Protein, msp23 Protein, nkefa Protein, pag Protein, paga Protein, pagb Protein, prx-1 Protein, prxi Protein, tdpx2 Protein, hm:zehl0637 Protein, zgc:110343 Protein, TPX-2 Protein, peroxiredoxin 1 Protein, peroxiredoxin 1 S homeolog Protein, peroxiredoxin-1 pseudogene Protein, PRDX1 Protein, Prdx1 Protein, prdx1.S Protein, prdx1 Protein, LOC100350232 Protein
- Background
- Prdx1, also known as peroxiredoxin-1, is an important member of peroxiredoxins (Prdxs) regulating various cellular signaling and differentiation. It confers an aggressive survival phenotype of cancer cells and drug-resistance. This protein is also identified as a red blood cell factor which enhances natural killer (NK) cell activity. Recombinant mouse Prdx1, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
- Molecular Weight
- 23.2kDa (207aa) 18-28KDa (SDS-PAGE under reducing conditions.)
- NCBI Accession
- NP_035164
- UniProt
- P35700
- Pathways
- p53 Signaling, EGFR Signaling Pathway, CXCR4-mediated Signaling Events
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