Interleukin 11 Receptor, alpha Chain 1 (IL11RA1) (AA 24-371) protein (His tag)
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- Target See all Interleukin 11 Receptor, alpha Chain 1 (IL11RA1) Proteins
- Interleukin 11 Receptor, alpha Chain 1 (IL11RA1)
- Protein Type
- Recombinant
- Protein Characteristics
- AA 24-371
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Origin
- Human
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Source
- Baculovirus infected Insect Cells
- Purification tag / Conjugate
- His tag
- Application
- SDS-PAGE (SDS)
- Sequence
- LEASEEVELE PCLAPSLEQQ EQELTVALGQ PVRLCCGRAE RGGHWYKEGS RLAPAGRVRG WRGRLEIASF LPEDAGRYLC LARGSMIVLQ NLTLITGDSL TSSNDDEDPK SHRDPSNRHS YPQQAPYWTH PQRMEKKLHA VPAGNTVKFR CPAAGNPTPT IRWLKDGQAF HGENRIGGIR LRHQHWSLVM ESVVPSDRGT YTCLVENAVG SIRYNYLLDV LERSPHRPIL QAGLPANTTA VVGSDVELLC KVYSDAQPHI QWLKHIVING SSFGADGFPY VQVLKTADIN SSEVEVLYLR NVSAEDAGEY TCLAGNSIGL SYQSAWLTVL PEEDPTWTAA APEARYTDLE HHHHHH
- Purity
- > 90 % by SDS - PAGE
- Endotoxin Level
- < 1.0 EU per 1 microgram of protein (determined by LAL method)
- Top Product
- Discover our top product IL11RA1 Protein
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Interleukin 11 Receptor, alpha Chain 1 (IL11RA1) (AA 24-372) protein (His tag)
Crystallography grade IL11RA1 Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, ELISA, Crys, WB
Interleukin 11 Receptor, alpha Chain 1 (IL11RA1) (AA 24-432) protein (rho-1D4 tag)Crystallography grade IL11RA1 Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, ELISA, Crys, WB
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.25 mg/mL
- Buffer
- Liquid. In Phosphate Buffered Saline ( pH 7.4) containing 10 % glycerol
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
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- Target
- Interleukin 11 Receptor, alpha Chain 1 (IL11RA1)
- Alternative Name
- IL11ra1 (IL11RA1 Products)
- Synonyms
- AI314697 Protein, GP130 Protein, Il-11ra Protein, Il11ra Protein, Il11ra2 Protein, NR1 Protein, interleukin 11 receptor, alpha chain 1 Protein, interleukin 11 receptor subunit alpha 1 Protein, Il11ra1 Protein
- Background
- FGFR4, as known as fibroblast growth factor receptor 4 isoform 1, is a glycosylated transmembrane receptor tyrosine kinase. This protein is widely expressed during embryonic development and in adult liver, kidney, and lung. Also, it is associates with beta-Klotho and sulfated glycosaminoglycans, and these interactions increase the affinity of FGFR4 for its ligands as well as its signaling capacity. This receptor signaling is additionally required for skeletal muscle development in limbs. Recombinant human FGFR4, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
- Molecular Weight
- 39.5kDa (356aa) 40-57kDa (SDS-PAGE under reducing conditions)
- NCBI Accession
- NP_002002
- UniProt
- P22455
- Pathways
- Growth Factor Binding
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