NCR1 Protein (AA 17-255) (hIgG-His-tag)
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- Target See all NCR1 Proteins
- NCR1 (Natural Cytotoxicity Triggering Receptor 1 (NCR1))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 17-255
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Origin
- Mouse
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Source
- Baculovirus infected Insect Cells
- Purification tag / Conjugate
- This NCR1 protein is labelled with hIgG-His-tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- ADLQRINTEK ETLPKPIIWA KPSIMVTNGN SVNIWCQGAQ SASEYQLYFE GSFFALERPK PSRSMNKVRF FISQMTSHTA GIYTCFYQSG ELWSKSSNPL KLVVTGLYDT PNLWVYPRPE VTLGENVTFF CQLKTATSKF FLLKERGSNH IQNKYGNIQA EFPMGPVTRA HRGTYRCFGS YNDYAWSFPS EPVTLLITGG VENSSLAPTD PTSSLDYWEF DLSTNESGLQ KDSAFWDHTT QNLEPKSCDK THTCPPCPAP ELLGGPSVFL FPPKPKDTLM ISRTPEVTCV VVDVSHEDPE VKFNWYVDGV EVHNAKTKPR EEQYNSTYRV VSVLTVLHQD WLNGKEYKCK VSNKALPAPI EKTISKAKGQ PREPQVYTLP PSRDELTKNQ VSLTCLVKGF YPSDIAVEWE SNGQPENNYK TTPPVLDSDG SFFLYSKLTV DKSRWQQGNV FSCSVMHEAL HNHYTQKSLS LSPGKHHHHH H
- Purity
- > 85 % by SDS - PAGE
- Endotoxin Level
- < 1.0 EU per 1 microgram of protein (determined by LAL method)
- Top Product
- Discover our top product NCR1 Protein
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.25 mg/mL
- Buffer
- Liquid. In Phosphate Buffered Saline ( pH 7.4) containing 10 % glycerol.
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
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- Target
- NCR1 (Natural Cytotoxicity Triggering Receptor 1 (NCR1))
- Alternative Name
- Ncr1 (NCR1 Products)
- Synonyms
- CD335 Protein, LY94 Protein, NK-p46 Protein, NKP46 Protein, Ly94 Protein, NKp46 Protein, KILR-1 Protein, Nk-p46 Protein, Nkp46 Protein, natural cytotoxicity triggering receptor 1 Protein, NCR1 Protein, Ncr1 Protein
- Background
- Ncr1, as known as natural cytotoxicity triggering receptor 1, is a natural killer cell p46-related protein. This protein, along with NKp30 and NKp44, are activiting receptors that belongs to the natural cytotoxicity receptor family. These receptors are expressed by NK cells in the peripheral blood and spleen expresses NKp46 in both resting and activated states. Also, it may contribute to the increased efficiency of activated NK cells to meditate tumor cell lysis. Recombinant mouse Ncr1, fused to hIgG-His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
- Molecular Weight
- 54.4kDa (481aa) 50-70kDa (SDS-PAGE under reducing conditions.)
- NCBI Accession
- NP_034876
- UniProt
- Q8C567
- Pathways
- Regulation of Leukocyte Mediated Immunity
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