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NCR1 Protein (AA 17-255) (hIgG-His-tag)

NCR1 Origin: Mouse Host: Baculovirus infected Insect Cells Recombinant > 85 % by SDS - PAGE SDS
Catalog No. ABIN6387914
  • Target See all NCR1 Proteins
    NCR1 (Natural Cytotoxicity Triggering Receptor 1 (NCR1))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 17-255
    Origin
    • 12
    • 7
    • 5
    • 2
    • 1
    Mouse
    Source
    • 14
    • 3
    • 3
    • 3
    • 2
    • 2
    Baculovirus infected Insect Cells
    Purification tag / Conjugate
    This NCR1 protein is labelled with hIgG-His-tag.
    Application
    SDS-PAGE (SDS)
    Sequence
    ADLQRINTEK ETLPKPIIWA KPSIMVTNGN SVNIWCQGAQ SASEYQLYFE GSFFALERPK PSRSMNKVRF FISQMTSHTA GIYTCFYQSG ELWSKSSNPL KLVVTGLYDT PNLWVYPRPE VTLGENVTFF CQLKTATSKF FLLKERGSNH IQNKYGNIQA EFPMGPVTRA HRGTYRCFGS YNDYAWSFPS EPVTLLITGG VENSSLAPTD PTSSLDYWEF DLSTNESGLQ KDSAFWDHTT QNLEPKSCDK THTCPPCPAP ELLGGPSVFL FPPKPKDTLM ISRTPEVTCV VVDVSHEDPE VKFNWYVDGV EVHNAKTKPR EEQYNSTYRV VSVLTVLHQD WLNGKEYKCK VSNKALPAPI EKTISKAKGQ PREPQVYTLP PSRDELTKNQ VSLTCLVKGF YPSDIAVEWE SNGQPENNYK TTPPVLDSDG SFFLYSKLTV DKSRWQQGNV FSCSVMHEAL HNHYTQKSLS LSPGKHHHHH H
    Purity
    > 85 % by SDS - PAGE
    Endotoxin Level
    < 1.0 EU per 1 microgram of protein (determined by LAL method)
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  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.25 mg/mL
    Buffer
    Liquid. In Phosphate Buffered Saline (  pH 7.4) containing 10 % glycerol.
    Storage
    4 °C,-20 °C,-80 °C
    Storage Comment
    Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
  • Target
    NCR1 (Natural Cytotoxicity Triggering Receptor 1 (NCR1))
    Alternative Name
    Ncr1 (NCR1 Products)
    Synonyms
    CD335 Protein, LY94 Protein, NK-p46 Protein, NKP46 Protein, Ly94 Protein, NKp46 Protein, KILR-1 Protein, Nk-p46 Protein, Nkp46 Protein, natural cytotoxicity triggering receptor 1 Protein, NCR1 Protein, Ncr1 Protein
    Background
    Ncr1, as known as natural cytotoxicity triggering receptor 1, is a natural killer cell p46-related protein. This protein, along with NKp30 and NKp44, are activiting receptors that belongs to the natural cytotoxicity receptor family. These receptors are expressed by NK cells in the peripheral blood and spleen expresses NKp46 in both resting and activated states. Also, it may contribute to the increased efficiency of activated NK cells to meditate tumor cell lysis. Recombinant mouse Ncr1, fused to hIgG-His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
    Molecular Weight
    54.4kDa (481aa) 50-70kDa (SDS-PAGE under reducing conditions.)
    NCBI Accession
    NP_034876
    UniProt
    Q8C567
    Pathways
    Regulation of Leukocyte Mediated Immunity
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