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SFRP4 Protein (AA 19-346) (His tag)

SFRP4 Origin: Human Host: Baculovirus infected Insect Cells Recombinant > 90 % by SDS - PAGE SDS
Catalog No. ABIN6387920
  • Target See all SFRP4 Proteins
    SFRP4 (Secreted Frizzled-Related Protein 4 (SFRP4))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 19-346
    Origin
    • 6
    • 4
    • 4
    • 1
    Human
    Source
    • 8
    • 2
    • 2
    • 1
    • 1
    • 1
    Baculovirus infected Insect Cells
    Purification tag / Conjugate
    This SFRP4 protein is labelled with His tag.
    Application
    SDS-PAGE (SDS)
    Sequence
    ADPVRGAPCE AVRIPMCRHM PWNITRMPNH LHHSTQENAI LAIEQYEELV DVNCSAVLRF FLCAMYAPIC TLEFLHDPIK PCKSVCQRAR DDCEPLMKMY NHSWPESLAC DELPVYDRGV CISPEAIVTD LPEDVKWIDI TPDMMVQERP LDVDCKRLSP DRCKCKKVKP TLATYLSKNY SYVIHAKIKA VQRSGCNEVT TVVDVKEIFK SSSPIPRTQV PLITNSSCQC PHILPHQDVL IMCYEWRSRM MLLENCLVEK WRDQLSKRSI QWEERLQEQR RTVQDKKKTA GRTSRSNPPK PKGKPPAPKP ASPKKNIKTR SAQKRTNPKR VHHHHHH
    Purity
    > 90 % by SDS - PAGE
    Endotoxin Level
    < 1.0 EU per 1 microgram of protein (determined by LAL method)
    Top Product
    Discover our top product SFRP4 Protein
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.5 mg/mL
    Buffer
    Liquid. In Phosphate Buffered Saline (  pH 7.4) containing 10 % glycerol.
    Storage
    4 °C,-20 °C,-80 °C
    Storage Comment
    Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
  • Target
    SFRP4 (Secreted Frizzled-Related Protein 4 (SFRP4))
    Alternative Name
    SFRP4 (SFRP4 Products)
    Synonyms
    SFRP4 Protein, FRP-4 Protein, FRPHE Protein, sFRP-4 Protein, secreted frizzled related protein 4 Protein, secreted frizzled-related protein 4 Protein, SFRP4 Protein, Sfrp4 Protein
    Background
    SFRP4, also known as secreted frizzled-related protein4, is a family of vertebrate proteins which contain homology to the ligand-binding domain of the Frizzled family of transmembrane receptors. It is expressed in brain, kidney, lung, ovary, prostate, mammary gland and endometrium. This protein act as soluble modulators of Wnt signaling, counteracting Wnt-induced effects at high concentrations and promoting them at lower concentrations. It is able to bind Wnt proteins and Frizzled receptors in the extracellular compartment. Recombinant human SFRP4, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
    Molecular Weight
    38.9kDa (337aa) 40-57KDa (SDS-PAGE under reducing conditions.)
    NCBI Accession
    NP_003005
    UniProt
    Q6FHJ7
    Pathways
    WNT Signaling
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