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DUSP23 Protein (AA 1-150) (His tag)

DUSP23 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % by SDS - PAGE SDS Active
Catalog No. ABIN6388007
  • Target See all DUSP23 Proteins
    DUSP23 (Dual Specificity Phosphatase 23 (DUSP23))
    Protein Type
    Recombinant
    Biological Activity
    Active
    Protein Characteristics
    AA 1-150
    Origin
    • 5
    • 1
    Human
    Source
    • 2
    • 2
    • 1
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This DUSP23 protein is labelled with His tag.
    Application
    SDS-PAGE (SDS)
    Sequence
    MGSSHHHHHH SSGLVPRGSH MGVQPPNFSW VLPGRLAGLA LPRLPAHYQF LLDLGVRHLV SLTERGPPHS DSCPGLTLHR LRIPDFCPPA PDQIDRFVQI VDEANARGEA VGVHCALGFG RTGTMLACYL VKERGLAAGD AIAEIRRLRP GSIETYEQEK AVFQFYQRTK
    Purity
    > 90 % by SDS - PAGE
    Biological Activity Comment
    Specific activity is > 200 units/mg, and is defined as the amount of enzyme that hydrolyze 1.0 nmole of p-nitrophenyl phosphate (pNPP) per minute at pH 7.5 at 37C.
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  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Comment

    Bioactivity Validated

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Liquid. In 20  mM Tris-HCl buffer (  pH 8.0) containing 2  mM DTT, 10 % glycerol, 100  mM NaCl
    Storage
    4 °C,-20 °C,-80 °C
    Storage Comment
    Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
  • Target
    DUSP23 (Dual Specificity Phosphatase 23 (DUSP23))
    Alternative Name
    DUSP23 (DUSP23 Products)
    Synonyms
    DUSP23 Protein, vhz Protein, mosp Protein, ldp-3 Protein, dusp25 Protein, DUSP25 Protein, LDP-3 Protein, MOSP Protein, RP11-190A12.1 Protein, VHZ Protein, 1300005N15Rik Protein, dual specificity phosphatase 23 Protein, dual specificity phosphatase 23 L homeolog Protein, Dusp23 Protein, DUSP23 Protein, dusp23.L Protein, dusp23 Protein
    Background
    DUSP23, also known as low molecular mass dual specificity phosphatase 3(LDP-3), belongs to the protein-tyrosine phosphatase family. This protein is a protein phosphatase that mediates dephosphorylation of proteins phosphorylated on Tyr and Ser/Thr residues. In vitro, it can dephosphorylate p44-ERK1 (MAPK3) but not p54 SAPK-beta (MAPK10) in vitro. This protein able to enhance activation of JNK and p38(MAPK14). Recombinant human DUSP23 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
    Molecular Weight
    18.8kDa (170aa), confirmed by MALDI-TOF
    NCBI Accession
    NP_060293
    UniProt
    Q9BVJ7
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