CD160 Protein (CD160) (AA 27-159) (His tag)
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- Target See all CD160 Proteins
- CD160
- Protein Type
- Recombinant
- Protein Characteristics
- AA 27-159
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Origin
- Human
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Source
- Baculovirus infected Insect Cells
- Purification tag / Conjugate
- This CD160 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- ADLINITSSA SQEGTRLNLI CTVWHKKEEA EGFVVFLCKD RSGDCSPETS LKQLRLKRDP GIDGVGEISS QLMFTISQVT PLHSGTYQCC ARSQKSGIRL QGHFFSILFT ETGNYTVTGL KQRQHLEFSH NEGTLSHHHH HH
- Purity
- > 90 % by SDS - PAGE
- Endotoxin Level
- < 1.0 EU per 1 microgram of protein (determined by LAL method)
- Top Product
- Discover our top product CD160 Protein
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.25 mg/mL
- Buffer
- Liquid. In Phosphate Buffered Saline ( pH 7.4) containing 10 % glycerol.
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
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- Target
- CD160
- Alternative Name
- CD160 (CD160 Products)
- Synonyms
- CD160 Protein, RGD1563598 Protein, BY55 Protein, AU045688 Protein, By55 Protein, NK1 Protein, NK28 Protein, CD160 molecule Protein, CD160 antigen Protein, CD160 Protein, Cd160 Protein
- Background
- CD160, also known as CD160 antigen, is a human natural killer (NK)-cell-activating receptor that is also expressed on T-cell subsets. It is a tumor-specific antigen known to mediate cellular activation signals in CLL, and is a novel target for therapeutic manipulation and monitoring of minimal residual disease. It was identified as a T cell coinhibitory molecule that interacts with the herpesvirus entry mediator (HVEM) on antigen-presenting cells to deliver a potent inhibitory signal to CD4(+) T cells. Recombinant human CD160, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
- Molecular Weight
- 15.9kDa (142aa) 18-28kDa (SDS-PAGE under reducing conditions)
- NCBI Accession
- NP_008984
- UniProt
- O95971
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