Peroxiredoxin 2 Protein (PRDX2) (AA 1-198) (His tag)
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- Target See all Peroxiredoxin 2 (PRDX2) Proteins
- Peroxiredoxin 2 (PRDX2)
- Protein Type
- Recombinant
- Biological Activity
- Active
- Protein Characteristics
- AA 1-198
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This Peroxiredoxin 2 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- MGSSHHHHHH SSGLVPRGSH MGSHMASGNA QIGKSAPDFT ATAVVDGAFK EIKLSDYRGK YVVLFFYPLD FTFVCPTEII AFSDHAEDFR KLGCEVLGVS VDSQFTHLAW INTPRKEGGL GPLNIPLLAD VTKSLSQNYG VLKNDEGIAY RGLFIIDAKG VLRQITVNDL PVGRSVDEAL RLVQAFQYTD EHGEVCPAGW KPGSDTIKPN VDDSKEYFSK HN
- Purity
- > 90 % by SDS - PAGE
- Biological Activity Comment
- Specific activity is > 700 pmol/min/ug, Activity is defined as the amount of hydroperoxide that 1ug of enzyme can reduce at 25C for minute.
- Top Product
- Discover our top product PRDX2 Protein
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Comment
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Bioactivity Validated
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Liquid. In 20 mM Tris-HCl buffer ( pH 8.0) containing 10 % Glycerol, 1 mM DTT
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
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- Target
- Peroxiredoxin 2 (PRDX2)
- Alternative Name
- Prdx2 (PRDX2 Products)
- Synonyms
- NKEF-B Protein, NKEFB Protein, PRP Protein, PRX2 Protein, PRXII Protein, PTX1 Protein, TDPX1 Protein, TPX1 Protein, TSA Protein, AL022839 Protein, Band-8 Protein, NkefB Protein, PrxII Protein, TDX1 Protein, TPx Protein, TPx-B Protein, TR Protein, Tdpx1 Protein, Torin Protein, nkefb Protein, prx-2 Protein, prx2 Protein, prxii Protein, tdpx1 Protein, tpx1 Protein, peroxiredoxin 2 Protein, peroxiredoxin 2 L homeolog Protein, PRDX2 Protein, Prdx2 Protein, prdx2.L Protein
- Background
- Prdx2, also known as peroxiredoxin-2, is a member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. Prdx2 may play an antioxidant protective role in cells, and may contribute to the antiviral activity of CD8(+) T-cells. If Prdx2 protection is inadequate against peroxidases, the resulting protein and DNA damage may result in neurological disease such as Alzheimer's or DNA damage leading to cancer. Recombinant mouse Prdx2, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
- Molecular Weight
- 24.3 kDa (222aa) Confirmed by MALDI-TOF
- NCBI Accession
- NP_035693
- UniProt
- Q61171
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