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MYDGF Protein (AA 25-166) (His tag)

D17Wsu104e Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % by SDS - PAGE SDS
Catalog No. ABIN6388124
  • Target See all MYDGF (D17Wsu104e) Proteins
    MYDGF (D17Wsu104e) (DNA segment, Chr 17, Wayne State University 104, expressed (D17Wsu104e))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 25-166
    Origin
    • 3
    • 2
    Human
    Source
    • 4
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This MYDGF protein is labelled with His tag.
    Application
    SDS-PAGE (SDS)
    Sequence
    MGSSHHHHHH SSGLVPRGSH MGSVSEPTTV PFDVRPGGVV HSFSQDVGPG NKFTCTFTYA SQGGTNEQWQ MSLGTSEDSQ HFTCTIWRPQ GKSYLYFTQF KAELRGAEIE YAMAYSKAAF ERESDVPLKS EEFEVTKTAV SHRPGAFKAE LSKLVIVAKA ARSEL
    Purity
    > 95 % by SDS - PAGE
    Top Product
    Discover our top product D17Wsu104e Protein
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.5 mg/mL
    Buffer
    Liquid. In 20  mM Tris-HCl(  pH 8.0) containing 0.1M NaCl, 10 % glycerol
    Storage
    4 °C,-20 °C,-80 °C
    Storage Comment
    Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
  • Target
    MYDGF (D17Wsu104e) (DNA segment, Chr 17, Wayne State University 104, expressed (D17Wsu104e))
    Alternative Name
    Mydgf (D17Wsu104e Products)
    Synonyms
    EUROIMAGE1875335 Protein, IL25 Protein, IL27 Protein, IL27w Protein, R33729_1 Protein, SF20 Protein, Il25 Protein, Ly6elg Protein, myeloid derived growth factor Protein, MYDGF Protein, Mydgf Protein
    Background
    Mydgf, also known as Myeloid-derived growth factor, is a bone marrow-derived monocyte and paracrine-acting protein that promotes cardiac myocyte survival and adaptive angiogenesis for cardiac protection and repair after myocardial infarction. It stimulates endothelial cell proliferation through a MAPK1/3-, STAT3- and CCND1-mediated signaling pathway. Mydgf-deficient mice develop larger infarct scars and more severe contractile dysfunction compared to wild-type mice. Recombinant mouse Mydgf, fused to His-tag at N-termineus, was expressed in E. coli and purified by using conventional chromatography techniques.
    Molecular Weight
    18.1 kDa (165aa) Confirmed by MALDI-TOF
    NCBI Accession
    NP_543027
    UniProt
    Q9CPT4
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