SEPSECS Protein (AA 1-504) (His tag)

Catalog No. ABIN6388235

Product Details

Target: SEPSECS (Sep (O-phosphoserine) tRNA:Sec (Selenocysteine) tRNA Synthase (SEPSECS))

Protein Type: Recombinant

Protein Characteristics: AA 1-504

Origin: Mouse

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This SEPSECS protein is labelled with His tag.

Application: SDS-PAGE (SDS)

Sequence: MGSSHHHHHH SSGLVPRGSH MGSMNPESFA AGERRVSPAY VRQGCEARRA HEHLIRLLLE QGKCPEDGWD ESTLELFLHE LAVMDSNNFL GNCGVGEREG RVASALVARR HYRFIHGIGR SGDISAVQPK AAGSSLLNKI TNSLVLNVIK LAGVHSVASC FVVPMATGMS LTLCFLTLRH KRPKAKYIIW PRIDQKSCFK SMVTAGFEPV VIENVLEGDE LRTDLKAVEA KIQELGPEHI LCLHSTTACF APRVPDRLEE LAVICANYDI PHVVNNAYGL QSSKCMHLIQ QGARVGRIDA FVQSLDKNFM VPVGGAIIAG FNEPFIQDIS KMYPGRASAS PSLDVLITLL SLGCSGYRKL LKERKEMFVY LSTQLKKLAE AHNERLLQTP HNPISLAMTL KTIDGHHDKA VTQLGSMLFT RQVSGARAVP LGNVQTVSGH TFRGFMSHAD NYPCAYLNAA AAIGMKMQDV DLFIKRLDKC LNIVRKEQTR ASVVSGADRN KAEDADIEEM ALKLDDVLGD VGQGPAL

Purity: > 90 % by SDS - PAGE

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: Liquid. In 20  mM Tris-HCl buffer (  pH 7.5) containing 1  mM DTT, 0.2M NaCl, 50 % Glycerol

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.

Target Details

Target: SEPSECS (Sep (O-phosphoserine) tRNA:Sec (Selenocysteine) tRNA Synthase (SEPSECS))

Alternative Name: Sepsecs (SEPSECS Products)

Synonyms: LP Protein, PCH2D Protein, SLA Protein, SLA/LP Protein, 9130208G10 Protein, AA986712 Protein, D5Ertd135e Protein, SecS Protein, sla/lpl Protein, zgc:55980 Protein, sepsecs Protein, Sep (O-phosphoserine) tRNA:Sec (selenocysteine) tRNA synthase Protein, Sep (O-phosphoserine) tRNA:Sec (selenocysteine) tRNA synthase L homeolog Protein, SEPSECS Protein, Sepsecs Protein, sepsecs Protein, sepsecs.L Protein

Target Type: Antibody

Background: Sepsecs, also known as O-phosphoseryl-tRNA (Sec) selenium transferase, catalyzes the final step of sec synthesis by converting O-phosphoseryl-tRNA (sec) to selenocysteinyl-tRNA (sec) using selenophosphate as the selenium donor. Also, this protein is considered a specific marker of autoimmune hepatitis. Recombinant mouse Sepsecs protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Molecular Weight: 57.7 kDa (527aa), confirmed by MALDI-TOF

NCBI Accession: NP_766078

UniProt: Q6P6M7

Pathways: SARS-CoV-2 Protein Interactome