FOXO3 Protein (AA 372-673) (His-SUMO Tag)
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- Target See all FOXO3 Proteins
- FOXO3 (Forkhead Box O3 (FOXO3))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 372-673
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This FOXO3 protein is labelled with His-SUMO Tag.
- Sequence
- MAGTMNLNDG LTENLMDDLL DNITLPPSQP SPTGGLMQRS SSFPYTTKGS GLGSPTSSFN STVFGPSSLN SLRQSPMQTI QENKPATFSS MSHYGNQTLQ DLLTSDSLSH SDVMMTQSDP LMSQASTAVS AQNSRRNVML RNDPMMSFAA QPNQGSLVNQ NLLHHQHQTQ GALGGSRALS NSVSNMGLSE SSSLGSAKHQ QQSPVSQSMQ TLSDSLSGSS LYSTSANLPV MGHEKFPSDL DLDMFNGSLE CDMESIIRSE LMDADGLDFN FDSLISTQNV VGLNVGNFTG AKQASSQSWV PG
- Characteristics
- N-terminal 6xHis-SUMO-tagged
- Purity
- Greater than 85% as determined by SDS-PAGE.
- Top Product
- Discover our top product FOXO3 Protein
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Forkhead Box O3 (FOXO3) (AA 1-673) protein (GST tag)
FOXO3 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Forkhead Box O3 (FOXO3) (AA 478-673) protein (His-IF2DI Tag)FOXO3 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Forkhead Box O3 (FOXO3) (AA 361-460) protein (GST tag)FOXO3 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Forkhead Box O3 (FOXO3) (AA 1-673) protein (Strep Tag)Crystallography grade FOXO3 Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
Forkhead Box O3 (FOXO3) (AA 1-672) protein (Strep Tag)Crystallography grade FOXO3 Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
Forkhead Box O3 (FOXO3) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)FOXO3 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Forkhead Box O3 (FOXO3) (Transcript Variant 2) protein (Myc-DYKDDDDK Tag)FOXO3 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.1-2 mg/mL
- Buffer
- 20 mM Tris-HCl based buffer, pH 8.0
- Storage
- -80 °C,4 °C,-20 °C
- Storage Comment
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- Target
- FOXO3 (Forkhead Box O3 (FOXO3))
- Alternative Name
- FOXO3 (FOXO3 Products)
- Synonyms
- AF6q21 Protein, FKHRL1 Protein, FKHRL1P2 Protein, FOXO2 Protein, FOXO3A Protein, zgc:92176 Protein, wu:fb50g02 Protein, wu:fi33f07 Protein, Fkhrl1 Protein, Foxo3a Protein, FoxO3A Protein, 1110048B16Rik Protein, 2010203A17Rik Protein, C76856 Protein, Fkhr2 Protein, FOXO-3 Protein, FOXO3 Protein, foxo3a Protein, xfoxo3 Protein, foxO3 Protein, foxO Protein, fkhr Protein, foxo5 Protein, wu:fj65a12 Protein, zFkhr Protein, forkhead box O3 Protein, forkhead box O3A Protein, forkhead box O3 L homeolog Protein, forkhead box O3b Protein, FOXO3 Protein, foxo3a Protein, Foxo3 Protein, foxo3.L Protein, foxo3 Protein, foxO3 Protein, foxo3b Protein
- Background
- Transcriptional activator which triggers apoptosis in the absence of survival factors, including neuronal cell death upon oxidative stress. Recognizes and binds to the DNA sequence 5'-[AG]TAAA[TC]A-3'. Participates in post-transcriptional regulation of MYC: following phosphorylation by MAPKAPK5, promotes induction of miR-34b and miR-34c expression, 2 post-transcriptional regulators of MYC that bind to the 3'UTR of MYC transcript and prevent its translation.
- Molecular Weight
- 48.1 kDa
- UniProt
- O43524
- Pathways
- Cell Division Cycle, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Carbohydrate Homeostasis
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