Interferon Regulatory Factor 2 (IRF2) (AA 1-113) protein (His tag)

Details for Product No. ABIN666699, Supplier: Log in to see
Protein Name
  • IRF-2
  • 9830146E22Rik
  • AI646973
  • Irf-2
  • irf2b
  • zgc:103451
  • irf-2
  • interferon regulatory factor 2
  • interferon regulatory factor 2 L homeolog
  • IRF2
  • Irf2
  • irf2
  • irf2.L
Protein Characteristics
AA 1-113
4
2
1
1
1
1
Origin
Human
10
2
1
Source
Escherichia coli (E. coli)
6
2
2
1
1
1
Protein Type
Recombinant
Purification tag / Conjugate
His tag
Application
SDS-PAGE (SDS)
Options
Supplier
Log in to see
Supplier Product No.
Log in to see
Characteristics IRF2 , 1-113 aa, Human, His-tagged, Recombinant, E.coli
Purity > 95 % by SDS - PAGE
Background Interferon regulatory factor (IRF) 2 is a member of the interferon regulatory transcription factor family. IRF-2 is generally regarded as an oncoprotein. Structure of IRF1 and IRF2 are similar. However, its functions are different. IRF2 competitively inhibits the IRF1-mediated transcriptional activation of interferons alpha and beta, and presumably other genes that employ IRF1 for transcription activation. Recombinant human IRF2 was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: Interferon regulatory factor 2, DKFZp686F0244, IRF2, IRF2, 1-113 aa His-tagged, IRF-2, Interferon regulatory factor-2 IRF 2. NCBI no.: NM_002190
Molecular Weight 15 kDa ( 133 aa), confirmed by MALDI-TOF.
Restrictions For Research Use only
Format Liquid
Concentration 1 mg/ml (determined by Bradford assay)
Buffer In 20mM Tris 8.0, 1mM DTT, 10% Glycerol
Storage 4 °C
Supplier Images
SDS-PAGE (SDS) image for Interferon Regulatory Factor 2 (IRF2) (AA 1-113) protein (His tag) (ABIN666699) Interferon Regulatory Factor 2 (IRF2) (AA 1-113) protein (His tag)
Background publications Matsuyama, Kimura, Kitagawa, Pfeffer, Kawakami, Watanabe, Kündig, Amakawa, Kishihara, Wakeham: "Targeted disruption of IRF-1 or IRF-2 results in abnormal type I IFN gene induction and aberrant lymphocyte development." in: Cell, Vol. 75, Issue 1, pp. 83-97, 1993 (PubMed).

Harada, Fujita, Miyamoto, Kimura, Maruyama, Furia, Miyata, Taniguchi: "Structurally similar but functionally distinct factors, IRF-1 and IRF-2, bind to the same regulatory elements of IFN and IFN-inducible genes." in: Cell, Vol. 58, Issue 4, pp. 729-39, 1989 (PubMed).

Did you look for something else?