Cofilin Protein (AA 1-166) (His tag)

Catalog No. ABIN666701

This Recombinant Cofilin protein is produced in Escherichia coli (E. coli).

Quick Overview for Cofilin Protein (AA 1-166) (His tag) (ABIN666701)

Target: Cofilin (CFL1) (Cofilin 1 (CFL1))

Protein Type: Recombinant

Origin: Human

Source: Escherichia coli (E. coli)

Application: SDS-PAGE (SDS)

Purity: > 95 % by SDS - PAGE

Product Details

Protein Characteristics: AA 1-166

Purification tag / Conjugate: This Cofilin protein is labelled with His tag.

Characteristics: Cofilin 1, 1-166 aa, Human, His-tagged, Recombinant, E.coli

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/ml (determined by Bradford assay)

Buffer: 20mM Tris pH 8.0, 10% Glycerol

Storage: 4 °C

Target Details

Target: Cofilin (CFL1) (Cofilin 1 (CFL1))

Alternative Name: Cofilin 1

Background: Cofilin is a family of actin-binding proteins which disassembles actin filaments. It is a widely distributed intracellular actin-modulating protein that binds and depolymerizes filamentous F-actin and inhibits the polymerization of monomeric G-actin in a pH-dependent manner. It is involved in the translocation of actin-cofilin complex from cytoplasm to nucleus. Recombinant human Cofilin, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: CFL1, CFL, Cofilin 1, CFL1, CFL, 18 kDa phosphoprotein(p18) 18 kDa phosphoprotein, CFL 1, Cofilin 1, Cofilin 1 non muscle, Cofilin non muscle isoform, P18. NCBI no.: NP _005498

Molecular Weight: 20kDa (186aa), confirmed by MALDI-TOF.

Pathways: Regulation of Cell Size, Tube Formation, Protein targeting to Nucleus, CXCR4-mediated Signaling Events