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GNMT Protein (AA 1-295) (His tag)

GNMT Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % by SDS - PAGE SDS
Catalog No. ABIN666718
  • Target See all GNMT Proteins
    GNMT (Glycine N-Methyltransferase (GNMT))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 1-295
    Origin
    • 10
    • 1
    • 1
    • 1
    Human
    Source
    • 6
    • 2
    • 2
    • 2
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This GNMT protein is labelled with His tag.
    Application
    SDS-PAGE (SDS)
    Characteristics
    GNMT, 1-295aa, Human,His-Tagged, Recombinant, E.coli
    Purity
    > 95 % by SDS - PAGE
    Top Product
    Discover our top product GNMT Protein
  • Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/ml (determined by Bradford assay)
    Buffer
    Liquid in 20mM Tris pH 8.0, 20% glycerol
    Storage
    4 °C
  • Target
    GNMT (Glycine N-Methyltransferase (GNMT))
    Alternative Name
    GNMT (GNMT Products)
    Background
    Glycine N-methyltransferase, also known as GNMT, catalyzes the synthesis of N-methylglycine (sarcosine) from glycine using S-adenosylmethionine (AdoMet) as the methyl donor. This protein affects DNA methylation by regulating the ratio of S-adenosylmethionine to S-adenosylhomocystine and participates in the detoxification pathway in liver cells. Also it is reported that GNMT expression is diminished in human hepatocellular carcinoma (HCC). Recombinant human GNMT protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: GNMT, Glycine N-methyltransferase, Glycine N-methyltransferase EC 2.1.1.20, Glycine N methyltransferase. NCBI no.: NP_061833
    Molecular Weight
    34.9kDa (315aa), confirmed by MALDI-TOF.
    Pathways
    Cellular Glucan Metabolic Process, Regulation of Carbohydrate Metabolic Process
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