Complexin 1 Protein (CPLX1) (AA 1-134) (His tag)
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- Target See all Complexin 1 (CPLX1) Proteins
- Complexin 1 (CPLX1)
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-134
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This Complexin 1 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Characteristics
- Complexin1, 1-134aa, Human, His tagged, Recombinant, E.coli
- Purity
- > 90 % by SDS - PAGE
- Top Product
- Discover our top product CPLX1 Protein
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Complexin 1 (CPLX1) (AA 1-134) protein (GST tag)
CPLX1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Complexin 1 (CPLX1) (AA 1-134) protein (Strep Tag)Crystallography grade CPLX1 Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA
Complexin 1 (CPLX1) protein (Myc-DYKDDDDK Tag)CPLX1 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/ml (determined by Bradford assay)
- Buffer
- Liquid. In 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol
- Storage
- 4 °C
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- Target
- Complexin 1 (CPLX1)
- Alternative Name
- Complexin1 (CPLX1 Products)
- Synonyms
- MGC84299 Protein, CPLX1 Protein, CPX-I Protein, CPX1 Protein, 921-S Protein, complexin 1 L homeolog Protein, complexin 1 Protein, cplx1.L Protein, CPLX1 Protein, cplx1 Protein, Cplx1 Protein
- Background
- Complexin1 belongs to a family of SNARE complex binding proteins that were suggested to be either facilitators or inhibitors of vesicle exocytosis. Complexin 1 exhibits reduced Ca2+-triggered fast neurotransmitter release at hippocampal glutamatergic synapses, indicating that this protein is a positive regulator of transmitter release. In contrast, it inhibits SNARE-mediated liposome and cell fusions in vitro, which lead to the hypothesis that it acts as fusion clamps of synaptic exocytosis. Recombinant Complexin 1 protein was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: CPXL1, CPX1, Synaphin-2, Complexin 1, Complexin I, CPX1, Synaphin 2,. NCBI no.: NP_006642
- Molecular Weight
- 17.1 kDa (154 aa), confirmed by MALDI-TOF. (Molecular weight on SDS-PAGE will appear higher)
- Pathways
- Hormone Transport, Synaptic Vesicle Exocytosis, Dicarboxylic Acid Transport
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