FH Protein (AA 44-510)
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- Target See all FH Proteins
- FH (Fumarate Hydratase (FH))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 44-510
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Application
- SDS-PAGE (SDS)
- Characteristics
- Fumarase, 44-510aa, Human, Recombinant, E.coli
- Purity
- > 95 % by SDS - PAGE
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Fumarate Hydratase (FH) (AA 33-510) protein (GST tag)
FH Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Fumarate Hydratase (FH) (AA 45-510) protein (His tag)Crystallography grade FH Origin: Human Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Fumarate Hydratase (FH) (AA 42-507) protein (His tag)Crystallography grade FH Origin: Mouse Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Fumarate Hydratase (FH) protein (Myc-DYKDDDDK Tag)FH Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/ml (determined by Bradford assay)
- Buffer
- Liquid. In 20 mM Tris-HCl buffer (pH 8.0)
- Storage
- 4 °C
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- Target
- FH (Fumarate Hydratase (FH))
- Alternative Name
- Fumarase (FH Products)
- Synonyms
- FH Protein, DDBDRAFT_0205237 Protein, DDBDRAFT_0231397 Protein, DDBDRAFT_0231400 Protein, DDB_0205237 Protein, DDB_0231397 Protein, DDB_0231400 Protein, HLRCC Protein, LRCC Protein, MCL Protein, MCUL1 Protein, Fh1 Protein, im:7152785 Protein, ns:zf-e152 Protein, zf-e152 Protein, zgc:66253 Protein, zgc:77498 Protein, Fh Protein, Fh-1 Protein, fumarate hydratase Protein, fumarate hydratase 1 Protein, FH Protein, fumH Protein, Fh Protein, fh Protein, Fh1 Protein
- Background
- Fumarase (Fumarate hytdratase) is an enzyme that catalyzes the reversible hydration/dehydration of fumarate to S-malate and is involved in the tricarboxylic acid (TCA), or Krebs cycle. This enzyme exists in both a cytosolic form and an N-terminal extended mitochondrial form. The N-terminal extended form is targeted to the mitochondrion, where the removal of the extension is the same form as in the cytoplasm. Fumarase deficiency can lead to progressive encephalopathy, cerebral atrophy and developmental delay and this enzyme also is thought to act as a tumor suppressor. Recombinant Fumarase was expressed in E.coli and was purified by conventional chromatography techniques. Synonyms: FH, HLRCC, LRCC, MCL, MCUL1 , Fumarate hydratase Fumarase, Fumarate hydratase mitochondrial, MCUL 1, Multiple hereditary cutaneous leiomyomata. NCBI no.: NP_000134
- Molecular Weight
- 50.2kDa (467aa), confirmed by MALDI-TOF.
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