PINX1 Protein (AA 1-328) (His tag)

Catalog No. ABIN666767

Product Details

Target: PINX1 (PIN2/TERF1 Interacting, Telomerase Inhibitor 1 (PINX1))

Protein Type: Recombinant

Protein Characteristics: AA 1-328

Origin: Human

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This PINX1 protein is labelled with His tag.

Application: SDS-PAGE (SDS)

Characteristics: PINX1, 1-328aa, Human, His-tagged, Recombinant, E.coli

Purity: > 95 % by SDS - PAGE

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/ml (determined by Bradford assay)

Buffer: : Liquid. In 20 mM Tris-HCl buffer (pH 8.0) containing, 1mM DTT, 10% glycerol

Storage: 4 °C

Target Details

Target: PINX1 (PIN2/TERF1 Interacting, Telomerase Inhibitor 1 (PINX1))

Alternative Name: PINX1 (PINX1 Products)

Synonyms: PINX1 Protein, LPTL Protein, LPTS Protein, 2210403I16Rik Protein, 2610028A01Rik Protein, 67-11-3 Protein, AU024023 Protein, LPTS1 Protein, RGD1566025 Protein, PIN2/TERF1 interacting telomerase inhibitor 1 Protein, PIN2/TERF1 interacting, telomerase inhibitor 1 Protein, PINX1 Protein, Pinx1 Protein

Background: PINX1(PIN2-interacting protein 1) is a ubiquitously expressed protein that localizes to nucleoli and telomere speckles. This protein contains a TID (telomerase inhibiting domain) domain which is capable of binding MCRS1, TERT and TERF1. PINX1 has been shown to be a potent telomerase inhibitor and putative tumor suppressor. Recombinant human PINX1, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography. Synonyms: PIN2-interacting protein 1, TRF1-interacting protein 1, Liver-related putative tumor suppressor, Protein 67-11-3, LPTL, LPTS, PINX1, PIN2-interacting protein 1 67-11-3 protein PIN2 interacting protein 1, Hepatocellular carcinoma-related putative tumor suppressor,. NCBI no.: NP_060354

Molecular Weight: 39.1 kDa (348aa), confirmed by MALDI-TOF.