BMF Protein (AA 1-129) (T7 tag)
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- Target See all BMF Proteins
- BMF (Bcl2 Modifying Factor (BMF))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-129
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This BMF protein is labelled with T7 tag.
- Application
- SDS-PAGE (SDS)
- Characteristics
- BMF, 1-129aa, Human, T7-tagged, Recombinant, E.coli
- Purity
- > 90 % by SDS - PAGE
- Top Product
- Discover our top product BMF Protein
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/ml (determined by Bradford assay)
- Buffer
- Liquid. In 20 mM Tris-HCl buffer (pH 7.5) containing, 1mM DTT, 10% glycerol
- Storage
- 4 °C
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- Target
- BMF (Bcl2 Modifying Factor (BMF))
- Alternative Name
- BMF (BMF Products)
- Background
- Bcl2 modifying factor, also known as BMF belongs to the Bcl2 protein family of apoptosis mediators. Bmf is constitutively expressed in many tissues. This protein contains a single Bcl2 homology domain 3 (BH3), and has been shown to bind Bcl2 proteins and function as an apoptotic activator. Also, BMF is a key molecule for histone deacetylase (HDAC) inhibitors which alters the balance between acetylation and deacetylation, significantly increasing histone acetylation, while strongly inducing apoptosis in a variety of cancer cell types. Recombinant human BMF, fused to T7-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography. Synonyms: Bcl2 modifying factor, isoform 3, BMF, Bcl2 modifying factor, isoform 3 Bcl 2 modifying factor, FLJ00065. NCBI no.: NP_001003943
- Molecular Weight
- 15.6 kDa (144aa), confirmed by MALDI-TOF.
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