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CITED2 Protein (AA 1-270) (His tag)

CITED2 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % by SDS - PAGE SDS
Catalog No. ABIN666771
  • Target See all CITED2 Proteins
    CITED2 (Cbp/p300-Interacting Transactivator, with Glu/Asp-Rich Carboxy-terminal Domain, 2 (CITED2))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 1-270
    Origin
    • 4
    • 1
    • 1
    • 1
    • 1
    Human
    Source
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This CITED2 protein is labelled with His tag.
    Application
    SDS-PAGE (SDS)
    Characteristics
    CITED2, 1- 270 aa, Human, His-tagged, Recombinant, E.coli
    Purity
    > 90 % by SDS - PAGE
  • Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.25 mg/ml (determined by Bradford assay)
    Buffer
    Liquid. In 20mM Tris-HCl buffer (pH8.0) containing 0.1M NaCl, 50% glycerol, 1mM DTT
    Storage
    4 °C
  • Target
    CITED2 (Cbp/p300-Interacting Transactivator, with Glu/Asp-Rich Carboxy-terminal Domain, 2 (CITED2))
    Alternative Name
    CITED2 (CITED2 Products)
    Synonyms
    mrg1 Protein, p35srj Protein, zgc:103418 Protein, CITED2 Protein, cite2 Protein, ASD8 Protein, MRG-1 Protein, MRG1 Protein, P35SRJ Protein, VSD2 Protein, AI835299 Protein, ER154-like Protein, Mrg1 Protein, Msg2 Protein, Cbp/p300-interacting transactivator, with Glu/Asp rich carboxy-terminal domain, 2 Protein, Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 Protein, Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2 Protein, Cbp/p300-interacting transactivator 2 Protein, Cbp/p300-interacting transactivator, with Glu/Asp rich carboxy-terminal domain, 2 L homeolog Protein, cited2 Protein, CITED2 Protein, cite2 Protein, Cited2 Protein, cited2.L Protein
    Background
    CITED2 is an important transcriptional cofactor involved in multiple organ development. It is a cAMP-responsive element-binding protein (CBP)/p300 interacting transcriptional modulator and a proposed negative regulator for hypoxia-inducible factor (HIF)-1alpha through its competitive binding with HIF-1alpha to CBP/p300. CITED2 is necessary for mouse fetal liver hematopoiesis and is required for the proper formation of the hyaloid vasculature and for lens morphogenesis. Recombinant CITED2 protein was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: Cbp/p300-interacting transactivator 2, MRG1, P35SRJ, CITED2, Cbp/p300-interacting transactivator 2 Cbp/p300 interacting transactivator 2, Cbp/p300 interacting transactivator with Glu/Asp rich carboxy terminal domain 2, MRG 1, MSG related protein 1,. NCBI no.: NP_006070
    Molecular Weight
    29.5 kDa (278 aa), confirmed by MALDI-TOF.
    Pathways
    Tube Formation
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