CITED2 Protein (AA 1-270) (His tag)
-
- Target See all CITED2 Proteins
- CITED2 (Cbp/p300-Interacting Transactivator, with Glu/Asp-Rich Carboxy-terminal Domain, 2 (CITED2))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-270
-
Origin
- Human
-
Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This CITED2 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Characteristics
- CITED2, 1- 270 aa, Human, His-tagged, Recombinant, E.coli
- Purity
- > 90 % by SDS - PAGE
-
-
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- 0.25 mg/ml (determined by Bradford assay)
- Buffer
- Liquid. In 20mM Tris-HCl buffer (pH8.0) containing 0.1M NaCl, 50% glycerol, 1mM DTT
- Storage
- 4 °C
-
- Target
- CITED2 (Cbp/p300-Interacting Transactivator, with Glu/Asp-Rich Carboxy-terminal Domain, 2 (CITED2))
- Alternative Name
- CITED2 (CITED2 Products)
- Synonyms
- mrg1 Protein, p35srj Protein, zgc:103418 Protein, CITED2 Protein, cite2 Protein, ASD8 Protein, MRG-1 Protein, MRG1 Protein, P35SRJ Protein, VSD2 Protein, AI835299 Protein, ER154-like Protein, Mrg1 Protein, Msg2 Protein, Cbp/p300-interacting transactivator, with Glu/Asp rich carboxy-terminal domain, 2 Protein, Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 Protein, Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2 Protein, Cbp/p300-interacting transactivator 2 Protein, Cbp/p300-interacting transactivator, with Glu/Asp rich carboxy-terminal domain, 2 L homeolog Protein, cited2 Protein, CITED2 Protein, cite2 Protein, Cited2 Protein, cited2.L Protein
- Background
- CITED2 is an important transcriptional cofactor involved in multiple organ development. It is a cAMP-responsive element-binding protein (CBP)/p300 interacting transcriptional modulator and a proposed negative regulator for hypoxia-inducible factor (HIF)-1alpha through its competitive binding with HIF-1alpha to CBP/p300. CITED2 is necessary for mouse fetal liver hematopoiesis and is required for the proper formation of the hyaloid vasculature and for lens morphogenesis. Recombinant CITED2 protein was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: Cbp/p300-interacting transactivator 2, MRG1, P35SRJ, CITED2, Cbp/p300-interacting transactivator 2 Cbp/p300 interacting transactivator 2, Cbp/p300 interacting transactivator with Glu/Asp rich carboxy terminal domain 2, MRG 1, MSG related protein 1,. NCBI no.: NP_006070
- Molecular Weight
- 29.5 kDa (278 aa), confirmed by MALDI-TOF.
- Pathways
- Tube Formation
-