Ataxin 3 Protein (ATXN3) (AA 1-370)
-
- Target See all Ataxin 3 (ATXN3) Proteins
- Ataxin 3 (ATXN3)
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-370
-
Origin
- Human
-
Source
- Escherichia coli (E. coli)
- Application
- SDS-PAGE (SDS)
- Characteristics
- Ataxin 3 , 1-370aa, Human, Recombinant, E.coli
- Purity
- > 90 % by SDS - PAGE
- Top Product
- Discover our top product ATXN3 Protein
-
Ataxin 3 (ATXN3) (AA 1-79) protein (GST tag)
ATXN3 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AA, AP
Ataxin 3 (ATXN3) (AA 1-370) protein (GST tag)ATXN3 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AA, AP
Ataxin 3 (ATXN3) (AA 1-355) protein (Strep Tag)Crystallography grade ATXN3 Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, SDS, WB
Ataxin 3 (ATXN3) (AA 1-364) protein (His tag)Crystallography grade ATXN3 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, SDS, WB, Crys
Ataxin 3 (ATXN3) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)ATXN3 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
-
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- 1 mg/ml (determined by Bradford assay)
- Buffer
- Liquid. In 20 mM Tris-HCl buffer (pH 7.5) containing 2mM DTT, 50mM NaCl, 10% glycerol.
- Storage
- 4 °C
-
- Target
- Ataxin 3 (ATXN3)
- Alternative Name
- Ataxin 3 (ATXN3 Products)
- Synonyms
- Mjd Protein, zgc:56323 Protein, ATXN3 Protein, at3 Protein, jos Protein, mjd Protein, atx3 Protein, mjd1 Protein, sca3 Protein, ataxin-3 Protein, MJD1 Protein, MGC83584 Protein, AT3 Protein, ATX3 Protein, JOS Protein, MJD Protein, SCA3 Protein, 2210008M02Rik Protein, AI463012 Protein, AI647473 Protein, Sca3 Protein, Rsca3 Protein, ataxin 3 Protein, ataxin 3 L homeolog Protein, ataxin-3 Protein, atxn3 Protein, ATXN3 Protein, atxn3.L Protein, MICPUN_104046 Protein, MICPUCDRAFT_46658 Protein, Atxn3 Protein
- Background
- Ataxin 3 is also known as Machado-Joseph disease protein 1. Machado–Joseph disease is one of several hereditary autosomal dominant neurodegenerative disorders. This protein contains trinucleotide CAG repeats in the coding region, and the expansion of these repeats from the normal 13-36 to 68-79 is the cause of Machado-Joseph disease. Ataxin 3 interacts with the major histone acetyltransferases cAMP-response-element binding protein (CREB)-binding protein, p300, and p300/CREB-binding protein-associated factor and inhibits transcription by these coactivators. Also, ataxin-3 is a proteasome-associated factor that mediates the degradation of ubiquitinated proteins. Recombinant human Ataxin-3 was expressed in E.coli and purified by using conventional chromatography. Synonyms: Ataxin 3, ATX3, MJD, MJD1, SCA3, ATXN3, JOS, ATXN3, AT3, EC 3.4.22., Josephin, Machado Joseph disease, Machado Joseph disease protein 1, Machado-Joseph disease protein 1 homolog, MJD gene, Rsca3, SCA3 gene, Spinocerebellar ataxia type 3 protein,. NCBI no.: AAH33711
- Molecular Weight
- 42.4 kDa (370aa), confirmed by MALDI-TOF.
-
