TCEB2 Protein (AA 1-118)
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- Target See all TCEB2 Proteins
- TCEB2 (Transcription Elongation Factor B (SIII), Polypeptide 2 (18kDa, Elongin B) (TCEB2))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-118
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Application
- SDS-PAGE (SDS)
- Characteristics
- Elongin B, 1-118aa, Human, Recombinant, E.coli
- Purity
- > 95 % by SDS - PAGE
- Top Product
- Discover our top product TCEB2 Protein
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/ml (determined by Bradford assay)
- Buffer
- Liquid. In 20 mM Tris-HCl buffer (pH 8.0) containing 1mMDTT, 0.1mM PMSF, 20% glycerol
- Storage
- 4 °C
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- Target
- TCEB2 (Transcription Elongation Factor B (SIII), Polypeptide 2 (18kDa, Elongin B) (TCEB2))
- Alternative Name
- Elongin B (TCEB2 Products)
- Synonyms
- 0610040H15Rik Protein, cb162 Protein, wu:fb47e08 Protein, ELOB Protein, SIII Protein, elongin B Protein, Elob Protein, elob Protein, ELOB Protein
- Background
- Elongin B , also known as TCEB2, is a subunit of the transcription factor B (SIII) complex. The SIII complex is a heterotrimer consisting of a transcriptionally active subunit (A) and two regulatory subunits (B and C). It activates elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites within transcription units. The von Hippel-Lindau tumor suppressor protein (pVHL) binds to elongins B and C, and thereby inhibits transcription elongation. Recombinant TCEB2 was expressed as insoluble protein aggregate in E.coli and purified by conventional chromatography, after refolding of the isolated inclusion bodies in a renaturation buffer. Synonyms: Elongin B, Transcription elongation factor B polypeptide 2, TCEB2, RNA polymerase II transcription factor SIII subunit B, SIII p18, EloB, Elongin 18 kDa subunit , EloB, TCEB 2, Transcription elongation factor B (SIII) polypeptide 2. NCBI no.: NP_009039
- Molecular Weight
- 13.1 kDa (118 aa), confirmed by MALDI-TOF.
- Pathways
- SARS-CoV-2 Protein Interactome
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