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RRAS2 Protein (AA 1-201) (His tag)

RRAS2 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % by SDS - PAGE SDS
Catalog No. ABIN666896
  • Target See all RRAS2 Proteins
    RRAS2 (Related RAS Viral (R-Ras) Oncogene Homolog 2 (RRAS2))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 1-201
    Origin
    • 4
    • 1
    Human
    Source
    • 3
    • 1
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This RRAS2 protein is labelled with His tag.
    Application
    SDS-PAGE (SDS)
    Characteristics
    RRAS2, 1- 201 aa, Human, His-tagged, Recombinant, E.coli
    Purity
    > 95 % by SDS - PAGE
  • Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.5 mg/ml (determined by Bradford assay)
    Buffer
    Liquid. In 20mM Tris-HCl buffer (pH8.0) containing 1mM DTT, 10% glycerol, 2mM EDTA
    Storage
    4 °C
  • Target
    RRAS2 (Related RAS Viral (R-Ras) Oncogene Homolog 2 (RRAS2))
    Alternative Name
    RRAS2 (RRAS2 Products)
    Synonyms
    TC21 Protein, 2610016H24Rik Protein, C86394 Protein, Ras-related protein R-Ras2 Protein, RAS related 2 Protein, related RAS viral (r-ras) oncogene 2 Protein, related RAS viral (r-ras) oncogene homolog 2 Protein, TVAG_453070 Protein, Bm1_46660 Protein, RRAS2 Protein, Rras2 Protein
    Background
    RAS viral (r-ras) oncogene homolog 2 isoform a, also known as RRAS2, belongs to the Ras like GTPase family that cycle between GTP-bound active and GDP-bound inactive states at the cytoplasmic face of the plasma membrane. It is implicated in the pathogenesis of human cancers. Thus, overexpression of active RRAS2 in EpH4 cells induces tumorigenicity through the phosphoinositide 3-kinase, p38 MAPK, and mTOR pathways, and these cells lose their sensitivity to the normal growth inhibitory role of TGF-beta. Recombinant human RRAS2, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: TC21, RAS viral (r-ras) oncogene homolog 2 isoform a C86394, Oncogene RRAS2, Oncogene TC21, Ras like protein TC21, Ras related protein R Ras2, Related RAS viral (r ras) oncogene homolog 2, Related RAS viral oncogene homolog 2, RRAS 2, TC 21, Teratocarcinoma oncogene, Teratocarcinoma oncogene TC21. NCBI no.: NP_036382
    Molecular Weight
    25.2 kDa (221aa), confirmed by MALDI-TOF.
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