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Ensa Protein (AA 1-121) (His tag)

ENSA Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % by SDS-PAGE SDS
Catalog No. ABIN666932
  • Target See all Ensa (ENSA) Proteins
    Ensa (ENSA) (Endosulfine alpha (ENSA))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 1-121
    Origin
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Source
    • 8
    • 5
    • 2
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This Ensa protein is labelled with His tag.
    Application
    SDS-PAGE (SDS)
    Characteristics
    ENSA, 1-121aa, Human, His tag, E.coli
    Purity
    > 90 % by SDS-PAGE
    Top Product
    Discover our top product ENSA Protein
  • Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/ml (determined by BCA)
    Buffer
    Liquid. In 20mM Tris buffer(pH 8.0) containing 10% glycerol, 1mM DTT.
    Storage
    4 °C
  • Target
    Ensa (ENSA) (Endosulfine alpha (ENSA))
    Alternative Name
    ENSA (ENSA Products)
    Synonyms
    ARPP-19e Protein, 1700020C18Rik Protein, 2610007F17Rik Protein, AI451924 Protein, ensa Protein, si:dkeyp-24a7.3 Protein, ensaa Protein, endosulfine alpha Protein, endosulfine alpha a Protein, endosulfine alpha S homeolog Protein, ENSA Protein, Ensa Protein, ensa Protein, ensaa Protein, ensa.S Protein
    Background
    ENSA, also known as alpha endosulfine, belongs to a highly conserved cAMP-regulated phosphoprotein (ARPP) family. This protein is expressed in a wide range of tissues including muscle, brain, and endocrine tissues. This protein was identified as an endogenous ligand for the sulfonylurea receptor, ABCC8/SUR1. ABCC8 is the regulatory subunit of the ATP-sensitive potassium (KATP) channel, which is located on the plasma membrane of pancreatic beta cells and plays a key role in the control of insulin release from pancreatic beta cells. This protein is thought to be an endogenous regulator of KATP channels. In vitro studies have demonstrated that this protein modulates insulin secretion through the interaction with KATP channel, and this gene has been proposed as a candidate gene for type 2 diabetes. Recombinant ENSA protein was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: ARPP-19e, Alpha endosulfine isoform 3 Alpha endosulfine, ARPP 19e, Endosulfine alpha. NCBI no.: NP_004427
    Molecular Weight
    15.5 kDa (141aa), confirmed by MALDI-TOF.
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