SGTA Protein (AA 1-313) (His tag)
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- Target See all SGTA Proteins
- SGTA (Small Glutamine-Rich Tetratricopeptide Repeat (TPR)-Containing, alpha (SGTA))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-313
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This SGTA protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Characteristics
- SGTA, 1-313 aa, Human, His-tagged, Recombinant, E.coli
- Purity
- > 95 % by SDS-PAGE
- Top Product
- Discover our top product SGTA Protein
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Small Glutamine-Rich Tetratricopeptide Repeat (TPR)-Containing, alpha (SGTA) (AA 1-313) protein (His tag)
SGTA Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE ELISA, WB
Small Glutamine-Rich Tetratricopeptide Repeat (TPR)-Containing, alpha (SGTA) (AA 42-123) protein (GST tag)SGTA Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
Small Glutamine-Rich Tetratricopeptide Repeat (TPR)-Containing, alpha (SGTA) (AA 1-313) protein (GST tag)SGTA Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
Small Glutamine-Rich Tetratricopeptide Repeat (TPR)-Containing, alpha (SGTA) (AA 1-315) protein (Strep Tag)Crystallography grade SGTA Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS
Small Glutamine-Rich Tetratricopeptide Repeat (TPR)-Containing, alpha (SGTA) protein (Myc-DYKDDDDK Tag)SGTA Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/ml (determined by Bradford assay)
- Buffer
- Liquid. In 20mM Tris-HCl buffer(pH 8.0) containing 10% glycerol 1mM DTT.
- Storage
- 4 °C
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- Target
- SGTA (Small Glutamine-Rich Tetratricopeptide Repeat (TPR)-Containing, alpha (SGTA))
- Alternative Name
- SGTA (SGTA Products)
- Synonyms
- sgta Protein, SGTA Protein, zgc:92462 Protein, SGT Protein, alphaSGT Protein, hSGT Protein, 5330427H01Rik Protein, AI194281 Protein, D10Ertd190e Protein, Sgt Protein, Stg Protein, small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha Protein, small glutamine rich tetratricopeptide repeat containing alpha Protein, small glutamine-rich tetratricopeptide repeat (TPR)-containing, beta Protein, small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha L homeolog Protein, sgta Protein, SGTA Protein, sgtb Protein, sgta.L Protein, Sgta Protein
- Background
- SGTA, also known as SGT or hSGT, is a ubiquitously expressed protein that contains three TPR protein-protein interaction repeats. This protien is believed to function as a component of the androgen receptor (AR)-chaperone-cochaperone complex, acting as a cochaperone involved in androgen signaling. In addition, SGTA functions as a cochaperone that binds directly to HSC70 and HSP70 and regulates their ATPase activity. On the basis of its role in apoptosis and androgen signaling, SGTA is a potential candidate for PCOS (polycystic ovary syndrome), a disorder characterized by androgen excess, obesity and menstrual disturbances. Recombinant SGTA protein, fused to His-tag at C-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: alphaSGT, hSGT, SGT, Small glutamine-rich tetratricopeptide repeat-containing protein alpha Small glutamine rich tetratricopeptide repeat TPR containing alpha, UBP, Vpu binding protein. NCBI no.: NP_003012
- Molecular Weight
- 35.1 kDa (321aa), confirmed by MALDI-TOF
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