NCK1 Protein (AA 1-377) (His tag)
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- Target See all NCK1 Proteins
- NCK1 (NCK Adaptor Protein 1 (NCK1))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-377
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This NCK1 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Characteristics
- NCK1, 1-377aa, Human, His tag, E.coli
- Purity
- > 90 % by SDS - PAGE
- Top Product
- Discover our top product NCK1 Protein
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NCK Adaptor Protein 1 (NCK1) (AA 1-377) protein (His tag)
NCK1 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
NCK Adaptor Protein 1 (NCK1) (AA 1-377) protein (GST tag)NCK1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
NCK Adaptor Protein 1 (NCK1) (AA 185-294) protein (GST tag)NCK1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
NCK Adaptor Protein 1 (NCK1) (AA 2-377) protein (His tag)Crystallography grade NCK1 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1mg/ml (determined by Bradford assay)
- Buffer
- Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 20% glycerol, 1mM EDTA, 50mM NaCl
- Storage
- 4 °C
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- Target
- NCK1 (NCK Adaptor Protein 1 (NCK1))
- Alternative Name
- NCK1 (NCK1 Products)
- Synonyms
- NCK Protein, NCKalpha Protein, nck-1 Protein, NCK1 Protein, 6330586M15Rik Protein, D230010O13Rik Protein, Nck Protein, Nck-1 Protein, Nck1 Protein, nck Protein, nck1-a Protein, nck1-b Protein, nckalpha Protein, NCK adaptor protein 1 Protein, non-catalytic region of tyrosine kinase adaptor protein 1 Protein, NCK adaptor protein 1b Protein, NCK adaptor protein 1 L homeolog Protein, NCK1 Protein, Nck1 Protein, nck1b Protein, nck1.L Protein
- Background
- NCK adaptor protein 1, also known as NCK, belongs to the adaptor family of proteins. The protein encoded by this gene is one of the signaling and transforming proteins containing Src homology 2 and 3 (SH2 and SH3) domains. It is located in the cytoplasm and is an adaptor protein involved in transducing signals from receptor tyrosine kinases to downstream signal recipients such as RAS. Overexpression of Nck resulted in transformation of NIH 3T3 and 3Y1 rat fibroblast. Recombinant human NCK1, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: NCK, NCKalpha, NCK adaptor protein 1 GRB4, melanoma NCK protein, MGC12668, NCK adaptor protein 2, NCK tyrosine kinase, NCKbeta, non catalytic region of tyrosine kinase, noncatalytic region of tyrosine kinase, beta, SH2/SH3 adaptor protein NCK alpha, SH2/SH3 adaptor protein NCK beta. NCBI no.: NP_006144
- Molecular Weight
- 45 kDa (397aa), confirmed by MALDI-TOF
- Pathways
- TCR Signaling, Regulation of Actin Filament Polymerization, Signaling Events mediated by VEGFR1 and VEGFR2, VEGFR1 Specific Signals
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