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HNMT Protein (AA 1-292) (His tag)

HNMT Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % by SDS - PAGE SDS
Catalog No. ABIN667093
  • Target See all HNMT Proteins
    HNMT (Histamine N-Methyltransferase (HNMT))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 1-292
    Origin
    • 6
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Source
    • 7
    • 3
    • 2
    • 2
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This HNMT protein is labelled with His tag.
    Application
    SDS-PAGE (SDS)
    Characteristics
    HNMT, 1-292 aa, Human, His-tagged, Recombinant, E.coli
    Purity
    > 95 % by SDS - PAGE
    Top Product
    Discover our top product HNMT Protein
  • Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/ml (determined by Bradford assay)
    Buffer
    Liquid. In 20mM Tris-HCl(pH8.0) buffer containing 10% glycerol
    Storage
    4 °C
  • Target
    HNMT (Histamine N-Methyltransferase (HNMT))
    Alternative Name
    HNMT (HNMT Products)
    Background
    Histamine N-methyltransferase (HNMT) is found in the cytosol and uses S-adenosyl-L-methionine as the methyl donor. HNMT inactivates histamine by N-methylation. Histamine is involved in regulation and modulation of immune response through the stimulation of four distinct subtypes of receptors, H1, H2, H3, and H4, present on the target cells. Histamine is inactivated by the histamine-metabolizing enzyme histamine N-methyltransferase (HNMT) in bronchus, kidney, and the central nervous system. It plays an important role in degrading histamine and in regulating the airway response to histamine. Recombinant human HNMT protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography. Synonyms: Histamine N-methyltransferase isoform 1 , HMT, HNMT-S1, HNMT-S2, Histamine N-methyltransferase isoform 1 EC 2.1.1.8, Histamine N methyltransferase, Hnmt, HNMT S1, HNMT S2. NCBI no.: NP_008826
    Molecular Weight
    37 kDa (328 aa), confirmed by MALDI-TOF.
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