HINT1 Protein (AA 1-126)
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- Target See all HINT1 Proteins
- HINT1 (Histidine Triad Nucleotide Binding Protein 1 (HINT1))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-126
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Application
- SDS-PAGE (SDS)
- Characteristics
- HINT1, 1-126 aa, Human, Recombinant, E.coli
- Purity
- > 90 % by SDS - PAGE
- Top Product
- Discover our top product HINT1 Protein
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/ml (determined by Bradford assay)
- Buffer
- Liquid. In 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol
- Storage
- 4 °C
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- Target
- HINT1 (Histidine Triad Nucleotide Binding Protein 1 (HINT1))
- Alternative Name
- HINT1 (HINT1 Products)
- Synonyms
- hint Protein, pkci-1 Protein, prkcnh1 Protein, HINT Protein, NMAN Protein, PKCI-1 Protein, PRKCNH1 Protein, AA673479 Protein, Hint Protein, Ipk1 Protein, Pkci Protein, Prkci Protein, zgc:103764 Protein, CHPKCI Protein, HINTZ Protein, PKCIZ Protein, histidine triad nucleotide binding protein 1 Protein, histidine triad nucleotide binding protein 1 S homeolog Protein, histidine triad nucleotide binding protein 1-Z Protein, Histidine triad nucleotide-binding protein 1 Protein, HINT1 Protein, hint1 Protein, Hint1 Protein, hint1.S Protein, HINT1Z Protein, hint-1 Protein
- Background
- HINT1, also known as Histidine triad nucleotide-binding protein 1, is a member of superfamily named for a near C-terminal HXHXHXX motif (H:Histidine, X:a hydrophobic amino acid) positioned at the alpha-phosphate of nucleotide substrates. This protein hydrolyzes adenosine 5'-monophosphoramidate substrates such as AMP-morpholidate, AMP-N-alanine methyl ester, AMP-alpha-acetyl lysine methyl ester and AMP-NH2. Although it was originally thought to be a protein kinase C inhibitor and act as a haplod-insufficient tumor suppressor including spontaneous tumor formation in Hint+/- and Hint-/- , its actual physiologic function is not known. Recombinant human HINT1 protein was expressed in E.coli and purified by using conventional chromatography. Synonyms: Histidine triad nucleotide-binding protein 1, HINT, PKCI-1, PRKCNH1, Histidine triad nucleotide-binding protein 1 Adenosine 5' monophosphoramidase, HINT 1, Histidine triad nucleotide binding protein 1, PKCI 1, PKCI1, Protein kinase C inhibitor 1, Protein kinase C interacting protein 1. NCBI no.: NP_005331
- Molecular Weight
- 13.8 kDa (126aa), confirmed by MALDI-TOF.
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