SCGN Protein (AA 1-276) (His tag)

Catalog No. ABIN667217

Product Details

Target: SCGN (Secretagogin, EF-Hand Calcium Binding Protein (SCGN))

Protein Type: Recombinant

Protein Characteristics: AA 1-276

Origin: Human

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This SCGN protein is labelled with His tag.

Application: SDS-PAGE (SDS)

Characteristics: SCGN, 1-276aa, Human, His tag, E.coli

Purity: > 90 % by SDS – PAGE

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/ml (determined by Bradford assay)

Buffer: Liquid. In 20mM Tris-HCl buffer(pH 8.0) containing 10% glycerol, 1mM DTT, 0.1M NaCl.

Storage: 4 °C

Target Details

Target: SCGN (Secretagogin, EF-Hand Calcium Binding Protein (SCGN))

Alternative Name: SCGN (SCGN Products)

Synonyms: SCGN Protein, MGC146683 Protein, CALBL Protein, DJ501N12.8 Protein, SECRET Protein, SEGN Protein, setagin Protein, zgc:100843 Protein, secretagogin, EF-hand calcium binding protein Protein, Secretagogin Protein, secretagogin, EF-hand calcium binding protein L homeolog Protein, SCGN Protein, scgn Protein, segn Protein, scgn.L Protein, Scgn Protein

Background: SCGN, also known as secretagogin, is a cytoplasmic protein that contains six EF-hand domains and is related to the calicium-binding proteins Calretinin and Calbindin D28K. This protein is thought to be involved in cell proliferation and KCl (potassium chloride)-mediated calcium flux events. Through its interaction with KCl and its subsequent ability to modulate calcium storage pools within the cell, SCGN may function to negatively control growth and differentiation rates and, thus, indirectly inhibit cell replication. Recombinant SCGN protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: CALBL, DJ501N12.8, SECRET, SEGN, setagin, Secretagogin. NCBI no.: NP_008929

Molecular Weight: 34.2 kDa (296aa), confirmed by MALDI-TOF